bamE:Quickview: Difference between revisions

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The Bam complex in ''E. coli'' consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA).  Letters have been assigned on the basis of molecular weight, from highest to lowest <ref name='LIB:EcoGene'/>.
The Bam complex in ''E. coli'' consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA).  Letters have been assigned on the basis of molecular weight, from highest to lowest <ref name='LIB:EcoGene'/>.
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smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.<ref name='LIB:EcoGene'/>





Revision as of 00:39, 3 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

smpA (synonyms: ECK2613, b2617, JW2598, smqA, bamE )[1][2]

Product(s)

SmpA product[1]: small membrane lipoprotein product, B2617 product, SmqA product; BamE product [2]

Description

SmpA small membrane protein A[3][4] Component of Outer Membrane Protein Assembly Complex[4]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): smpA[3]

Regulation/Activity


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See Help:Quickview for help with entering information in the Quickview table.

Notes

A consensus has been reached for renaming the genes that encode components of the outer membrane β-barrel assembly machine, (formerly known as the YaeT complex of E. coli or the Omp85 complex of N. meningitidis). The new designation for this multi-component structure is the Bam complex (for beta-barrel assembly machine).

The Bam complex in E. coli consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA). Letters have been assigned on the basis of molecular weight, from highest to lowest [2].

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smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.[2]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7