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<span style = 'font-size: large'> '''Dermody, JJ, Robinson, GT and Sternglanz, R''' (1979) Conditional-lethal deoxyribonucleic acid ligase mutant of Escherichia coli.''J. Bacteriol.'' '''139''':701-4</span> | |||
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|{{TableHeadingColor}} |'''Abstract''' || <protect>A new Escherichia coli deoxyribonucleic acid (DNA) ligase mutant has been identified among a collection of temperature-sensitive DNA replication mutants isolated recently (Sevastopoulos, Wehr, and Glaser, Proc. Natl. Acad. Sci. U.S.A. 74:3485-3489, 1977). At the nonpermissive temperature DNA synthesis in the mutant stops rapidly, the DNA is degraded to acid-soluble material, and cell death ensures. This suggests that the mutant may be among the most ligase-deficient strains yet characterized.</protect> | |||
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|{{TableHeadingColor}} nowrap |'''Links''' || [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=378985 PubMed]<br/> | |||
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Revision as of 03:19, 30 October 2008
Dermody, JJ, Robinson, GT and Sternglanz, R (1979) Conditional-lethal deoxyribonucleic acid ligase mutant of Escherichia coli.J. Bacteriol. 139:701-4
| Abstract | A new Escherichia coli deoxyribonucleic acid (DNA) ligase mutant has been identified among a collection of temperature-sensitive DNA replication mutants isolated recently (Sevastopoulos, Wehr, and Glaser, Proc. Natl. Acad. Sci. U.S.A. 74:3485-3489, 1977). At the nonpermissive temperature DNA synthesis in the mutant stops rapidly, the DNA is degraded to acid-soluble material, and cell death ensures. This suggests that the mutant may be among the most ligase-deficient strains yet characterized. |
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