Category:Txn unit:aroP: Difference between revisions

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'''Description''' (originally from EcoCyc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>) aroP
'''Description''' (originally from EcoCyc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>) aroP


'''Comments''' (originally from EcoCyc<ref name='LIB:EcoCyc11.1'/>) The aroPp2 promoter is partially repressed by TyrR alone; thisrepression is enhanced in the presence of tyrosine or phenylalanine <ref name='PMID:10515932'/><ref name='PMID:3025182'/><ref name='PMID:10515932'/><ref name='PMID:10515932'/><ref name='PMID:10515932'/>.
'''Comments''' (originally from EcoCyc<ref name='LIB:EcoCyc11.1'/>) The transcription from the aroPp1 promoter is repressed by the TyrRprotein by recruiting the RNA polymerase to a nonproductive promoterlocated divergently from the aroPp1 promoter overlapping it. The RNApolymerase cannot be bound to both promoters at the same time. Whilethis repression can be observed in the presence of tyrosine, a lesserrepression is seen in the presence of phenylalanine or tryptophan <ref name='PMID:9765583'/><ref name='PMID:3025182'/><ref name='PMID:9765583'/>.




==References==
==References==
<references/>
<references/>

Latest revision as of 05:32, 30 July 2007

About

Description (originally from EcoCyc[1][2]) aroP

Comments (originally from EcoCyc[2]) The transcription from the aroPp1 promoter is repressed by the TyrRprotein by recruiting the RNA polymerase to a nonproductive promoterlocated divergently from the aroPp1 promoter overlapping it. The RNApolymerase cannot be bound to both promoters at the same time. Whilethis repression can be observed in the presence of tyrosine, a lesserrepression is seen in the presence of phenylalanine or tryptophan [3][4][3].


References

  1. ↑ EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. ↑ 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 Wang, P et al. (1998) Demonstration that the TyrR protein and RNA polymerase complex formed at the divergent P3 promoter inhibits binding of RNA polymerase to the major promoter, P1, of the aroP gene of Escherichia coli. J. Bacteriol. 180 5466-72 PubMed
  4. ↑ Chye, ML & Pittard, J (1987) Transcription control of the aroP gene in Escherichia coli K-12: analysis of operator mutants. J. Bacteriol. 169 386-93 PubMed

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