Category:Txn unit:aroP

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Description (originally from EcoCyc[1][2]) aroP

Comments (originally from EcoCyc[2]) The transcription from the aroPp1 promoter is repressed by the TyrRprotein by recruiting the RNA polymerase to a nonproductive promoterlocated divergently from the aroPp1 promoter overlapping it. The RNApolymerase cannot be bound to both promoters at the same time. Whilethis repression can be observed in the presence of tyrosine, a lesserrepression is seen in the presence of phenylalanine or tryptophan [3][4][3].


References

  1. EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  2. 2.0 2.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 Wang, P et al. (1998) Demonstration that the TyrR protein and RNA polymerase complex formed at the divergent P3 promoter inhibits binding of RNA polymerase to the major promoter, P1, of the aroP gene of Escherichia coli. J. Bacteriol. 180 5466-72 PubMed
  4. Chye, ML & Pittard, J (1987) Transcription control of the aroP gene in Escherichia coli K-12: analysis of operator mutants. J. Bacteriol. 169 386-93 PubMed

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