Clusters of Orthologous Groups (COGs): Difference between revisions

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Revision as of 21:22, 9 July 2006

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Clusters of Orthologous Groups (COGs)
Who: NCBI
What: Phylogenetic classification of proteins encoded in complete genomes
Where: Clusters of Orthologous Groups (COGs)
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About Clusters of Orthologous Groups (COGs)

The Clusters of Orthologous Groups (COGs) of proteins were generated by comparing the protein sequences of complete genomes. Each cluster contains proteins or groups of paralogs from at least three lineages. The current COG database contains both prokaryotic and eukaryotic clusters.

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References

The COG database: an updated version includes eukaryotes.
Tatusov RL 'et al' BMC Bioinformatics. 2003 Sep 11;4:41. Epub 2003 Sep 11. Full Text

The COG database: a tool for genome-scale analysis of protein functions and evolution.
Tatusov RL 'et al' Nucleic Acids Res. 2000 Jan 1;28(1):33-6. Full Text

A genomic perspective on protein families.
Tatusov RL 'et al' Science. 1997 Oct 24;278(5338):631-7.Abstract

External Links

Clusters of Orthologous Groups (COGs)

Discussion of Clusters of Orthologous Groups (COGs) on other websites