PMID:6344786: Difference between revisions
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!align=left |Citation | |||
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'''Jaffé, A, Chabbert, YA and Derlot, E''' (1983) Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants. ''Antimicrob. Agents Chemother.'' '''23''':622-5 | |||
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!align=left |Abstract | |||
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beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles). | |||
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!align=left |Links | |||
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[http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=6344786 PubMed] [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC184714 PMC184714] | |||
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!align=left |Keywords | |||
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Anti-Bacterial Agents/pharmacology; Drug Resistance, Microbial; Escherichia coli/drug effects; Escherichia coli/genetics; Mutation; beta-Lactamases/biosynthesis; beta-Lactams | |||
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==Significance {{HelpIcon|Help:Literature}} == | |||
{{LitSignificance}} | |||
== Useful Materials and Methods {{HelpIcon|Help:Literature}}== | |||
{{LitMaterials}} | |||
==Annotations {{HelpIcon|Help:Literature}}== | |||
<annotationlinks/> | |||
==EcoliWiki Links {{HelpIcon|Help:Literature}} == | |||
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==See also== | |||
==References== | |||
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Latest revision as of 10:25, 19 February 2014
| Citation |
Jaffé, A, Chabbert, YA and Derlot, E (1983) Selection and characterization of beta-lactam-resistant Escherichia coli K-12 mutants. Antimicrob. Agents Chemother. 23:622-5 |
|---|---|
| Abstract |
beta-Lactam-resistant mutants of Escherichia coli K-12 were selected by using 12 different beta-lactam derivatives. The mutants fell into three categories showing (i) altered permeation through reduction or loss of outer membrane porin proteins (including ompF, ompR, and envZ alleles); (ii) increase in the rate of synthesis of chromosomally mediated beta-lactamase; or (iii) defective synthesis or action of cyclic adenosine 3',5'-phosphate (cya and crp alleles). |
| Links | |
| Keywords |
Anti-Bacterial Agents/pharmacology; Drug Resistance, Microbial; Escherichia coli/drug effects; Escherichia coli/genetics; Mutation; beta-Lactamases/biosynthesis; beta-Lactams |
| edit table |
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