folK:Quickview: Difference between revisions
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[http://ecoliwiki.net/tools/display_dna.php?gene=folK&loc=MG1655:157732..157253,W3110:157732..157253,DH10B:131836..131357,REL606:160583..160104 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start= | [http://ecoliwiki.net/tools/display_dna.php?gene=folK&loc=MG1655:157732..157253,W3110:157732..157253,DH10B:131836..131357,REL606:160583..160104,BW2952:157252..157731 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=157252&end=157731&gene=folK&aa=mtvayiaigsnlaspleqvnaalkalgdipeshiltvssfyrtpplgpqdqpdylnaavaletslapeellnhtqrielqqgrvrkaerwgprtldldimlfgnevinterltvphydmknrgfmlwplfeiapelvfpdgemlrqilhtrafdklnkw Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=folK+AND+escherichia+coli Pubmed(folK)] [http://trimer.tamu.edu/cgi-bin/textpresso/search?q=folK Textpresso(folK)] | ||
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Revision as of 15:35, 12 April 2011
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
folK |
|---|---|
| Gene Synonym(s) |
ECK0141, b0142, JW0138[1] |
| Product Desc. |
H2PTERIDINEPYROPHOSPHOKIN[2][3] 6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase; monomeric[4] |
| Product Synonyms(s) |
2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase[1], HPPK[2][1], B0142[2][1], FolK[2][1] |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
HPPK active center is formed once both substrates, ATP and HP, are bound and this assembly results in confirmational changes primarily in catalytic loops 1-3; catalytic loop 3 moves in the opposite direction upon binding of the nucleotide. Catalytic loop 3 is involved in ternary complex stabilization and is necessary for catalysis.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.