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predicted 2Fe-2S cluster-containing protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
predicted 2Fe-2S cluster-containing protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


6-N-hydroxylaminopurine resistance, function unknown<ref name='LIB:EcoGene'/>
6-N-hydroxylaminopurine resistance, Molybdenum cofactor binding protein<ref name='LIB:EcoGene'/><ref name='PMID:18312271'/><ref name='PMID:20118259'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)

Revision as of 21:46, 1 March 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ycbX

Gene Synonym(s)

ECK0938, b0947, JW5126[1]

Product Desc.

predicted 2Fe-2S cluster-containing protein[2][3]

6-N-hydroxylaminopurine resistance, Molybdenum cofactor binding protein[4][5][6]

Product Synonyms(s)

predicted 2Fe-2S cluster-containing protein[1], YcbX[2][1], B0947[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ycbX[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(ycbX)    Textpresso(ycbX)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Molybdenum cofactor (MoCo), YcbX and YiiM are involved in the detoxification of 6-N-hydroxylaminopurine (HAP), which proceeds by a reduction to adenine (Kozmin, 2008).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Kozmin, SG et al. (2008) YcbX and yiiM, two novel determinants for resistance of Escherichia coli to N-hydroxylated base analogues. Mol. Microbiol. 68 51-65 PubMed
  6. ↑ Kozmin, SG et al. (2010) Role for CysJ flavin reductase in molybdenum cofactor-dependent resistance of Escherichia coli to 6-N-hydroxylaminopurine. J. Bacteriol. 192 2026-33 PubMed