ycbX:Quickview

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Standard Name

ycbX

Gene Synonym(s)

ECK0938, b0947, JW5126[1], JW5126

Product Desc.

predicted 2Fe-2S cluster-containing protein[2][3]

6-N-hydroxylaminopurine resistance, Molybdenum cofactor binding protein[4][5][6]

Product Synonyms(s)

predicted 2Fe-2S cluster-containing protein[1], YcbX[2][1], B0947[2][1] , ECK0938, JW5126, b0947

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ycbX[2]

Regulation/Activity
Quick Links

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Notes

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Molybdenum cofactor (MoCo), YcbX and YiiM are involved in the detoxification of 6-N-hydroxylaminopurine (HAP), which proceeds by a reduction to adenine (Kozmin, 2008).[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Kozmin, SG et al. (2008) YcbX and yiiM, two novel determinants for resistance of Escherichia coli to N-hydroxylated base analogues. Mol. Microbiol. 68 51-65 PubMed
  6. Kozmin, SG et al. (2010) Role for CysJ flavin reductase in molybdenum cofactor-dependent resistance of Escherichia coli to 6-N-hydroxylaminopurine. J. Bacteriol. 192 2026-33 PubMed