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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
<GO_nr />
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
* GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0006744 ubiquinone biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype

Revision as of 19:37, 2 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ispG

Gene Synonym(s)

ECK2511, b2515, JW2499, gcpE[1]

Product Desc.

EG10370[2][3]

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein[4]

Product Synonyms(s)

1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase[1], B2515[2][1], GcpE[2][1], IspG[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(ispG)    Textpresso(ispG)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

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The IspG substrate is 2C-methyl-d-erythritol 2,4-cyclodiphosphate. In vitro activity requires auxiliary protein(s), probably as shuttles for redox equivalents. E. coli ispG(gcpE) complements the P. stuartii aarC1 defect in quorum sensing regulation of gene expression. The ispG gene is essential.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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