ampG:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''ampG''  
''ampG''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0427, b0433, JW0423''<ref name='LIB:Riley_2006'/>
''ECK0427, b0433, JW0423''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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AmpG muropeptide MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
AmpG muropeptide MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Muropeptide permease, imports GlcNAc-anhMurNAc-peptides; required for cloned Citrobacter freundii AmpR-regulated beta-lactamase induction and murein recycling<ref name='LIB:EcoGene'/>
Muropeptide permease, imports GlcNAc-anhMurNAc-peptides; required for cloned Citrobacter freundii AmpR-regulated beta-lactamase induction and murein recycling<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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muropeptide transporter<ref name='LIB:Riley_2006'/>, B0433<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AmpG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
muropeptide transporter<ref name='LIB:Riley_2006'/>, B0433<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AmpG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0000270 peptidoglycan metabolic process ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0015835 peptidoglycan transport ([http://www.geneontology.org/GO.evidence.shtml IGI])
'''Molecular Function'''
* GO:0015295 solute:hydrogen symporter activity ([http://www.geneontology.org/GO.evidence.shtml IGI])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ampG|ampG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ampG|ampG]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=ampG&loc=MG1655:452769..451294,W3110:452769..451294,DH10B:392100..390625,REL606:424250..422775 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=424250&end=422775&gene=ampG&aa=mssqylrifqqprsaillilgfasglplaltsgtlqawmtvenidlktigffslvgqayvfkflwsplmdrytppffgrrrgwllatqilllvaiaamgflepgtqlrwmaalavviafcsasqdivfdawktdvlpaeergagaaisvlgyrlgmlvsgglalwladkwlgwqgmywlmaallipciiatllapeptdtipvpktleqavvaplrdffgrnnawlilllivlyklgdafamsltttflirgvgfdagevgvvnktlgllativgalyggilmqrlslfrallifgilqgasnagywllsitdkhlysmgaavffenlcggmgtsafvallmtlcnksfsatqfallsalsavgrvyvgpvagwfveahgwstfylfsvaaavpglilllvcrqtleytrvndnfisrtaypagyafamwtlaagvsllavwlllltmdaldlthfsflpallevgvlvalsgvvlgglldylalrkthlt Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ampG+AND+escherichia+coli Pubmed(ampG)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=ampG Textpresso(ampG)]


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Revision as of 00:12, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ampG

Gene Synonym(s)

ECK0427, b0433, JW0423[1]

Product Desc.

AmpG muropeptide MFS transporter[2][3]

Muropeptide permease, imports GlcNAc-anhMurNAc-peptides; required for cloned Citrobacter freundii AmpR-regulated beta-lactamase induction and murein recycling[4]

Product Synonyms(s)

muropeptide transporter[1], B0433[2][1], AmpG[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ampG[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(ampG)    Textpresso(ampG)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Imported muropeptides must contain the disaccharide GlcNAc-anhMurNAc, which is also efficiently transported without attached peptides. Mutants accumulate GlcNAc-anhMurNAc-tripeptide. Transport inhibited by CCCP. 14 TM helices are [predicted, but fusion studies indicate that predicted hydrophobic helices 5, 6, 11, and 12 are in cytoplasmic loops; AmpG probably has 10 TM helices with N-in, C-in topology. AmpG has been studied using cloned Citrobacter freundii ampR and ampC genes, which are normally on the chromosome of C. freundii. This C. freundii ampC is not the same as the E. coli weak constitutive chromosomal ampC beta-lactamase; E. coli has no ampR gene. Major Facilitator Superfamily (MFS).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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