cysQ:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''cysQ''  
''cysQ''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4210, b4214, JW4172, amt, amtA''<ref name='LIB:Riley_2006'/>
''ECK4210, b4214, JW4172, amt, amtA''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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3'-phosphoadenosine 5'-phosphate (pAp) phosphatase; converts pAp to AMP; inhibited by lithium and calcium, leading to pAP accumulation; probable PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase: probably converts PAPS to<ref name='LIB:EcoGene'/>
3'-phosphoadenosine 5'-phosphate (pAp) phosphatase; converts pAp to AMP; inhibited by lithium and calcium, leading to pAP accumulation; probable PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase: probably converts PAPS to<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase product<ref name='LIB:Riley_2006'/>, B4214 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Amt product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AmtA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysQ product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase product<ref name='LIB:Riley_2006'/>, B4214 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Amt product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AmtA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CysQ product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0000103 sulfate assimilation ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0000287 magnesium ion binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Cellular Component'''
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IC])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:cysQ|cysQ]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:cysQ|cysQ]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=cysQ&loc=MG1655:4434778..4435518,W3110:4441435..4442175,REL606:4421749..4422489 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4421749&end=4422489&gene=cysQ&aa=mldqvcqlarnagdaimqvydgtkpmdvvskadnspvtaadiaahtvimdglrtltpdvpvlseedppgwevrqhwqrywlvdpldgtkefikrngeftvnialidhgkpilgvvyapvmnvmysaaegkawkeecgvrkqiqvrdarpplvvisrshadaelkeylqqlgehqttsigsslkfclvaegqaqlyprfgptniwdtaaghavaaaagahvhdwqgkpldytpresflnpgfrvsiy Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=cysQ+AND+escherichia+coli Pubmed(cysQ)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=cysQ Textpresso(cysQ)]


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Revision as of 00:05, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

cysQ

Gene Synonym(s)

ECK4210, b4214, JW4172, amt, amtA[1]

Product Desc.

affects pool of 3'-phosphoadenosine-5'-phosphosulfate in pathway of sulfite synthesis[2][3]

3'-phosphoadenosine 5'-phosphate (pAp) phosphatase; converts pAp to AMP; inhibited by lithium and calcium, leading to pAP accumulation; probable PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase: probably converts PAPS to[4]

Product Synonyms(s)

PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase product[1], B4214 product[2][1], Amt product[2][1], AmtA product[2][1], CysQ product[2][1]

Function from GO

Biological Process

Molecular Function

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): cysQ[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(cysQ)    Textpresso(cysQ)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


CysQ is a main target of lithium toxicity in vivo. CysQ (AmtA) was originally thought to be involved in ammonium transport. CysQ may be part of a futile sulfur cycle with APS kinase CysC.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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