folE:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''folE''  
''folE''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2146, b2153, JW2140''<ref name='LIB:Riley_2006'/>
''ECK2146, b2153, JW2140''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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GTP cyclohydrolase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
GTP cyclohydrolase I<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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GTP cyclohydrolase I<ref name='LIB:EcoGene'/>
GTP cyclohydrolase I<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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GTP cyclohydrolase I<ref name='LIB:Riley_2006'/>, B2153<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FolE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
GTP cyclohydrolase I<ref name='LIB:Riley_2006'/>, B2153<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FolE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0043234 protein complex ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0005525 GTP binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0008270 zinc ion binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0003934 GTP cyclohydrolase I activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Biological Process'''
* GO:0008616 queuosine biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0046656 folic acid biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:yeiB|yeiB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:yeiB|yeiB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=folE&loc=MG1655:2241674..2241006,W3110:2246986..2246318,REL606:2194890..2194222,DH10B:2332663..2331995 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2332663&end=2331995&gene=folE&aa=mpslskeaalvhealvargletplrppvhemdnetrksliaghmteimqllnldladdslmetphriakmyvdeifsgldyanfpkitlienkmkvdemvtvrditltstcehhfvtidgkatvayipkdsviglskinrivqffaqrpqvqerltqqilialqtllgtnnvavsidavhycvkargirdatsattttslgglfkssqntrheflravrhhn Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=folE+AND+escherichia+coli Pubmed(folE)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=folE Textpresso(folE)]


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Revision as of 23:58, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

folE

Gene Synonym(s)

ECK2146, b2153, JW2140[1]

Product Desc.

GTP cyclohydrolase I[2][3];

Component of GTP cyclohydrolase I[2][3]

GTP cyclohydrolase I[4]

Product Synonyms(s)

GTP cyclohydrolase I[1], B2153[2][1], FolE[2][1]

Function from GO

Cellular Component

Molecular Function

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yeiB[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(folE)    Textpresso(folE)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Although a folE null mutant could not be made by Baba (2006), leading to its inclusion in the set of 303 essential genes, Klaus (2005) were able to construct a deletion mutation in folE. It requires LB+ thymidine and grows poorly, explaining the Baba negative result. Thus, folE is not an essential gene. FolE is the first enzyme of pre-Q(0) biosynthesis (Phillips, 2008).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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