glnK:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''glnK'' | ''glnK'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0444, b0450, JW0440, ybaI''<ref name='LIB:Riley_2006'/> | ''ECK0444, b0450, JW0440, ybaI''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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[GlnK]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> , uridylyl-[GlnK]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | [GlnK]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> , uridylyl-[GlnK]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
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Potent activator of NRII(GlnL/NtrB) phosphatase; trimeric; regulated through NRI/NRII two-component regulatory system; binds to membrane when inhibiting AmtB<ref name='LIB:EcoGene'/> | Potent activator of NRII(GlnL/NtrB) phosphatase; trimeric; regulated through NRI/NRII two-component regulatory system; binds to membrane when inhibiting AmtB<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB<ref name='LIB:Riley_2006'/>, B0450<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YbaI<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,unmodified protein PII 2<ref name='LIB:EcoCyc10.6'/>, modified protein PII 2<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,[protein PII2]<ref name='LIB:EcoCyc10.6'/>, uridylyl-[protein PII2]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,PII2<ref name='LIB:EcoCyc10.6'/>, uridylyl-[PII2]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, | nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB<ref name='LIB:Riley_2006'/>, B0450<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YbaI<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,unmodified protein PII 2<ref name='LIB:EcoCyc10.6'/>, modified protein PII 2<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,[protein PII2]<ref name='LIB:EcoCyc10.6'/>, uridylyl-[protein PII2]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>,PII2<ref name='LIB:EcoCyc10.6'/>, uridylyl-[PII2]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:glnK-amtB|glnK-amtB]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:glnK-amtB|glnK-amtB]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=glnK&loc=MG1655:471822..472160,W3110:471822..472160,DH10B:411153..411491,REL606:444665..445003 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=444665&end=445003&gene=glnK&aa=mklvtviikpfkledvrealssigiqgltvtevkgfgrqkghaelyrgaeysvnflpkvkidvaiaddqldevidivskaaytgkigdgkifvaelqrvirirtgeadeaal Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=glnK+AND+escherichia+coli Pubmed(glnK)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=glnK Textpresso(glnK)] | |||
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Revision as of 23:55, 21 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
glnK |
|---|---|
| Gene Synonym(s) |
ECK0444, b0450, JW0440, ybaI[1] |
| Product Desc. |
[GlnK][2][3] , uridylyl-[GlnK][2][3] Component of nitrogen regulatory protein GlnK[2][3] Potent activator of NRII(GlnL/NtrB) phosphatase; trimeric; regulated through NRI/NRII two-component regulatory system; binds to membrane when inhibiting AmtB[4] |
| Product Synonyms(s) |
nitrogen assimilation regulatory protein for GlnL, GlnE, and AmtB[1], B0450[2][1], YbaI[2][1],unmodified protein PII 2[2], modified protein PII 2[2][1],[protein PII2][2], uridylyl-[protein PII2][2][1],PII2[2], uridylyl-[PII2][2][1], |
| Function from GO | |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
glnK is a glnB paralog. Like GlnB, the GlnK protein is a member of the trimeric PII signal transduction protein family. In nitrogen limitation it is subject to post-translational modification by uridylylation (mediated by GlnD) of Tyr51 in the T-loop of each subunit. This modification is reversed in N-sufficient conditions. In ammonium sufficient conditions non-uridylylated GlnK forms a 1:1 complex with the ammonia channel protein AmtB and prevents ammonium uptake through AmtB. Complex formation is reversed by ammonium starvation. [Comment provided by EcoTeam member Mike Merrick, 11.16.06][4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.