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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''groS''  
''groS''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB, tabA''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB, tabA''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Chaperonin Cpn10; GroESL small subunit GroES; phage morphogenesis<ref name='LIB:EcoGene'/>
Chaperonin Cpn10; GroESL small subunit GroES; phage morphogenesis<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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Cpn10 chaperonin GroES, small subunit of GroESL product<ref name='LIB:Riley_2006'/>, GroE product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4142 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hdh product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TabA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroS product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroES product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MopB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
Cpn10 chaperonin GroES, small subunit of GroESL product<ref name='LIB:Riley_2006'/>, GroE product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4142 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hdh product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TabA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroS product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GroES product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MopB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0044010 single-species biofilm formation ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0042963 phage assembly ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0009408 response to heat ([http://www.geneontology.org/GO.evidence.shtml IEP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:groS|groS]]<ref name='LIB:EcoCyc10.6'/>, groS, groES  
transcription unit(s): [[:Category:Txn_unit:groS|groS]]<ref name='LIB:EcoCyc10.6'/>, groS, groES  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=groS&loc=MG1655:4368711..4369004,W3110:4375368..4375661,DH10B:4469073..4469366,REL606:4458139..4458591,REL606:4349409..4349702 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4349409&end=4349702&gene=groS&aa=mnirplhdrvivkrkevetksaggivltgsaaakstrgevlavgngrilengevkpldvkvgdivifndgygvksekidneevlimsesdilaivea Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=groS+AND+escherichia+coli Pubmed(groS)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=groS Textpresso(groS)]


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Revision as of 23:54, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

groS

Gene Synonym(s)

ECK4136, b4142, JW4102, groES, mopA, groE, hdh, mopB, tabB, tabA[1][2]

Product Desc.

GroES, chaperone binds to Hsp60 in pres. Mg-ATP, suppressing its ATPase activity[2][3];

Component of GroEL-GroES Chaperonin-CPLX[3]

Chaperonin Cpn10; GroESL small subunit GroES; phage morphogenesis[4]

Product Synonyms(s)

Cpn10 chaperonin GroES, small subunit of GroESL product[1], GroE product[2][1], B4142 product[2][1], Hdh product[2][1], TabA product[2][1], GroS product[2][1], GroES product[2][1], MopB product[2][1]

Function from GO

Biological Process

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): groS[2], groS, groES

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(groS)    Textpresso(groS)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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GroS binds and regulates rpoH. Cells deficient in GroES and GroEL lyse due to inability to produce cell walls as a result of the reduced level of DapA, the first enzyme in the DAP synthesis pathway. Growth below 8C is impaired due to GroESL inactivation and can be rescued by transgenic Oleispira antarctica Cpn10/60. Overproduction of GroESL can supress tig/dnaK synthetic lethality at 30 degrees C. Binds TrxA (Kumar, 2004).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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