ispG:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''ispG'' | ''ispG'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK2511, b2515, JW2499, gcpE''<ref name='LIB:Riley_2006'/> | ''ECK2511, b2515, JW2499, gcpE''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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EG10370<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | EG10370<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
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1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein<ref name='LIB:EcoGene'/> | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase<ref name='LIB:Riley_2006'/>, B2515<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GcpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IspG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase<ref name='LIB:Riley_2006'/>, B2515<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GcpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IspG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI]) | |||
* GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
'''Biological Process''' | |||
* GO:0006744 ubiquinone biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): | transcription unit(s): | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=ispG&loc=MG1655:2639826..2638708,W3110:2640460..2639342,DH10B:2731591..2730473,REL606:2562623..2561505 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2562623&end=2561505&gene=ispG&aa=mhnqapiqrrkstriyvgnvpigdgapiavqsmtntrttdveatvnqikalervgadivrvsvptmdaaeafklikqqvnvplvadihfdyrialkvaeygvdclrinpgnigneerirmvvdcardknipirigvnagslekdlqekygeptpqallesamrhvdhldrlnfdqfkvsvkasdvflavesyrllakqidqplhlgiteaggarsgavksaiglglllsegigdtlrvslaadpveeikvgfdilkslrirsrginfiacptcsrqefdvigtvnaleqrlediitpmdvsiigcvvngpgealvstlgvtggnkksglyedgvrkdrldnndmidqlearirakasqldearridvqqvek Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ispG+AND+escherichia+coli Pubmed(ispG)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=ispG Textpresso(ispG)] | |||
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Revision as of 23:48, 21 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
ispG |
|---|---|
| Gene Synonym(s) |
ECK2511, b2515, JW2499, gcpE[1] |
| Product Desc. |
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; alternative nonmevalonate (DXP) pathway for terpenoid biosynthesis; [4Fe-4S] protein[4] |
| Product Synonyms(s) |
1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase[1], B2515[2][1], GcpE[2][1], IspG[2][1] |
| Function from GO |
Molecular Function
Biological Process
|
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
The IspG substrate is 2C-methyl-d-erythritol 2,4-cyclodiphosphate. In vitro activity requires auxiliary protein(s), probably as shuttles for redox equivalents. E. coli ispG(gcpE) complements the P. stuartii aarC1 defect in quorum sensing regulation of gene expression. The ispG gene is essential.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.