phoA:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''phoA'' | ''phoA'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0378, b0383, JW0374, psiA''<ref name='LIB:Riley_2006'/> | ''ECK0378, b0383, JW0374, psiA''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
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Alkaline phosphatase, periplasmic; binds Zn(II); dimeric<ref name='LIB:EcoGene'/> | Alkaline phosphatase, periplasmic; binds Zn(II); dimeric<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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bacterial alkaline phosphatase<ref name='LIB:Riley_2006'/>, B0383<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsiA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | bacterial alkaline phosphatase<ref name='LIB:Riley_2006'/>, B0383<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsiA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:phoA-psiF|phoA-psiF]]<ref name='LIB:EcoCyc10.6'/>, OP00071, phoA | transcription unit(s): [[:Category:Txn_unit:phoA-psiF|phoA-psiF]]<ref name='LIB:EcoCyc10.6'/>, OP00071, phoA | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=phoA&loc=MG1655:400971..402386,W3110:400971..402386,DH10B:340302..341717,REL606:369393..370808 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=369393&end=370808&gene=phoA&aa=mkqstialallpllftpvtkartpempvlenraaqgditapggarrltgdqtaalrdslsdkpakniilligdgmgdseitaarnyaegaggffkgidalpltgqythyalnkktgkpdyvtdsaasatawstgvktyngalgvdihekdhptilemakaaglatgnvstaelqdatpaalvahvtsrkcygpsatsekcpgnalekggkgsiteqllnaradvtlgggaktfaetatagewqgktlreqaqargyqlvsdaaslnsvteanqqkpllglfadgnmpvrwlgpkatyhgnidkpavtctpnpqrndsvptlaqmtdkaiellsknekgfflqvegasidkqdhaanpcgqigetvdldeavqralefakkegntlvivtadhahasqivapdtkapgltqalntkdgavmvmsygnseedsqehtgsqlriaaygphaanvvgltdqtdlfytmkaalglk Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=phoA+AND+escherichia+coli Pubmed(phoA)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=phoA Textpresso(phoA)] | |||
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Revision as of 00:32, 22 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
phoA |
|---|---|
| Gene Synonym(s) |
ECK0378, b0383, JW0374, psiA[1] |
| Product Desc. |
Component of alkaline phosphatase[2][3] Alkaline phosphatase, periplasmic; binds Zn(II); dimeric[4] |
| Product Synonyms(s) |
bacterial alkaline phosphatase[1], B0383[2][1], PsiA[2][1], PhoA[2][1] |
| Function from GO |
Molecular Function
|
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Arg22 is removed from the mature enzyme by Iap to form isozyme 3. Isozyme 2 is a heterodimer of isozymes 1 and 3 subunits. PhoA requires the reducing environment of the periplasm and DsbA for activity; cysteine bonds C190-C200 and C308-C358 are needed. PhoA fusions are used to indicate periplasmic location of hybrid proteins.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.