lptA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''lptA''  
''lptA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''yhbN, ECK3189, b3200, JW3167''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''yhbN, ECK3189, b3200, JW3167''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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LptA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
LptA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly<ref name='LIB:EcoGene'/>
Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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predicted transporter subunit: periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3200<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhbN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted transporter subunit: periplasmic-binding component of ABC superfamily<ref name='LIB:Riley_2006'/>, B3200<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YhbN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0015921 lipopolysaccharide export ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0017089 glycolipid transporter activity ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s):   
transcription unit(s):   
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=lptA&loc=MG1655:3341402..3341959,W3110:3343235..3343792,REL606:3278615..3279172 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3278615&end=3279172&gene=lptA&aa=mkfktnklslnlvlassllaasipafavtgdtdqpihiesdqqsldmqgnvvtftgnvivtqgtikinadkvvvtrpggeqgkevidgygkpatfyqmqdngkpveghasqmhyelakdfvvltgnaylqqvdsnikgdkitylvkeqkmqafsdkgkrvttvlvpsqlqdknnkgqtpaqkkgn Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=lptA+AND+escherichia+coli Pubmed(lptA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=lptA Textpresso(lptA)]


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Revision as of 23:46, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

lptA

Gene Synonym(s)

yhbN, ECK3189, b3200, JW3167[1][2]

Product Desc.

LptA[2][3];

Component of YhbG/YhbN ABC transporter[2]; LptA/LptB ABC transporter[3]

Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly[4]

Product Synonyms(s)

predicted transporter subunit: periplasmic-binding component of ABC superfamily[1], B3200[2][1], YhbN[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(lptA)    Textpresso(lptA)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


LptA depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Paralogous to Imp. The first 27 aa are a type I signal peptide. RpoE regulon.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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