lptA:Quickview

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References Suggestions

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Standard Name

lptA

Gene Synonym(s)

yhbN, ECK3189, b3200, JW3167[1][2], JW3167

Product Desc.

LptA[2][3];

Component of YhbG/YhbN ABC transporter[2]; LptA/LptB ABC transporter[3]

Periplasmic LPS-binding protein, binds Lipid A domain; LPS transport and assembly[4]

Product Synonyms(s)

predicted transporter subunit: periplasmic-binding component of ABC superfamily[1], B3200[2][1], YhbN[2][1] , ECK3189, JW3167, yhbN, b3200

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

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Notes

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LptA depletion results in rifampicin/bile salts sensitivity, indicative of an outer membrane integrity defect. Paralogous to Imp. The first 27 aa are a type I signal peptide. RpoE regulon.[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.