fis:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''fis'' | ''fis'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/> | ''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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Fis transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | Fis transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
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Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric<ref name='LIB:EcoGene'/> | Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:dusB-fis|dusB-fis]]<ref name='LIB:EcoCyc10.6'/>, OP00028, fis, yhdG-fis | transcription unit(s): [[:Category:Txn_unit:dusB-fis|dusB-fis]]<ref name='LIB:EcoCyc10.6'/>, OP00028, fis, yhdG-fis | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=fis&loc=MG1655:3409293..3409589,W3110:3411126..3411422,DH10B:3507038..3507334,REL606:3339162..3339458 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3339162&end=3339458&gene=fis&aa=mfeqrvnsdvltvstvnsqdqvtqkplrdsvkqalknyfaqlngqdvndlyelvlaeveqplldmvmqytrgnqtraalmmginrgtlrkklkkygmn Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=fis+AND+escherichia+coli Pubmed(fis)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=fis Textpresso(fis)] | |||
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Revision as of 00:00, 22 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
fis |
|---|---|
| Gene Synonym(s) |
ECK3248, b3261, JW3229, nbp[1] |
| Product Desc. |
Fis transcriptional dual regulator[2][3] Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric[4] |
| Product Synonyms(s) |
global DNA-binding transcriptional dual regulator[1], B3261[2][1], Nbp[2][1], Fis[2][1], site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription[2][1] |
| Function from GO |
Molecular Function
|
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
fis transcription is supercoiling-dependent. Overexpression causes filamentous biofilm formation. Decreased levels of Fis inhibit open complex formation, inhibiting oriC unwinding by blocking IHF and DnaA low affinity binding sites. Polyamine modulon. Mutations affect chromosomal supercoliing.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.