dksA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''dksA''  
''dksA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK0144, b0145, JW0141, msmA''<ref name='LIB:Riley_2006'/>
''ECK0144, b0145, JW0141, msmA''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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RNAP-binding transcriptional regulator of rRNA transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
RNAP-binding transcriptional regulator of rRNA transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters<ref name='LIB:EcoGene'/>
RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein<ref name='LIB:Riley_2006'/>, B0145<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsmA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DksA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein<ref name='LIB:Riley_2006'/>, B0145<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsmA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DksA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s):   
transcription unit(s):   
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=dksA&loc=MG1655:160604..160149,W3110:160604..160149,DH10B:134708..134253,REL606:163455..163000 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=163455&end=163000&gene=dksA&aa=mqegqnrktsslsilaiagvepyqekpgeeymneaqlahfrrileawrnqlrdevdrtvthmqdeaanfpdpvdraaqeeefslelrnrdrerklikkiektlkkvededfgycescgveigirrlearptadlcidcktlaeirekqmag Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=dksA+AND+escherichia+coli Pubmed(dksA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=dksA Textpresso(dksA)]


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Revision as of 00:03, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

dksA

Gene Synonym(s)

ECK0144, b0145, JW0141, msmA[1]

Product Desc.

RNAP-binding transcriptional regulator of rRNA transcription[2][3]

RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters[4]

Product Synonyms(s)

RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein[1], B0145[2][1], MsmA[2][1], DksA[2][1]

Function from GO

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(dksA)    Textpresso(dksA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


High copy dksA suppresses mukB and TS growth and filamentation of a dnaK mutant. dksA is also a multicopy suppressor of dnaJ, grpE and prc. dksA transcription is alkali-inducible. Mutations affect chromosomal supercoiling. Binds TrxA (Kumar, 2004). HT_Cmplx24_Cyt: DksA+GreA. dksA and ybiI are paralogs.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.