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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions


Standard Name


Gene Synonym(s)

ECK0144, b0145, JW0141, msmA[1], msmA

Product Desc.

RNAP-binding transcriptional regulator of rRNA transcription[2][3]

RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters[4]

Product Synonyms(s)

RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein[1], B0145[2][1], MsmA[2][1], DksA[2][1] , ECK0144, JW0141, msmA, b0145

Function from GO

<GO_nr />

Knock-Out Phenotype

transcription unit(s):

Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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High copy dksA suppresses mukB and TS growth and filamentation of a dnaK mutant. dksA is also a multicopy suppressor of dnaJ, grpE and prc. dksA transcription is alkali-inducible. Mutations affect chromosomal supercoiling. Binds TrxA (Kumar, 2004). HT_Cmplx24_Cyt: DksA+GreA. dksA and ybiI are paralogs.[4]


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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.