chbA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''chbA''  
''chbA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1734, b1736, JW1725, celC''<ref name='LIB:Riley_2006'/>
''ECK1734, b1736, JW1725, celC''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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ChbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
ChbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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PTS Enzyme IIA(Chb), N,N'-diacetylchitobiose utilization; trimeric<ref name='LIB:EcoGene'/>
PTS Enzyme IIA(Chb), N,N'-diacetylchitobiose utilization; trimeric<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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N,N'-diacetylchitobiose-specific enzyme IIA component of PTS<ref name='LIB:Riley_2006'/>, B1736<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ChbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CelC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
N,N'-diacetylchitobiose-specific enzyme IIA component of PTS<ref name='LIB:Riley_2006'/>, B1736<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ChbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, CelC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:chbBCARFG|chbBCARFG]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:chbBCARFG|chbBCARFG]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=chbA&loc=MG1655:1817829..1817479,W3110:1821519..1821169,DH10B:1908400..1908050 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1908400&end=1908050&gene=chbA&aa=mmdldnipdtqteaeeleevvmgliinsgqarslayaalkqakqgdfaaakammdqsrmalneahlvqtkliegdagegkmkvslvlvhaqdhlmtsmlarelitelielheklka Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=chbA+AND+escherichia+coli Pubmed(chbA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=chbA Textpresso(chbA)]


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Revision as of 00:07, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

chbA

Gene Synonym(s)

ECK1734, b1736, JW1725, celC[1]

Product Desc.

ChbA[2][3];

Component of EIIChb[2][3]

PTS Enzyme IIA(Chb), N,N'-diacetylchitobiose utilization; trimeric[4]

Product Synonyms(s)

N,N'-diacetylchitobiose-specific enzyme IIA component of PTS[1], B1736[2][1], ChbA[2][1], CelC[2][1]

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): chbBCARFG[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(chbA)    Textpresso(chbA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


The chb operon is induced by N,N'-diacetylchitobiose. The chb operon was previously thought to encode a cryptic cel operon for a cellobiose degradation system. The Cel+ phenotype is due to mutations making expression chitobiose-independent, but a fully induced operon did not support growth on cellobiose, implying a mutation altering the substrate specificity is needed; several candidate mutations were noted in Genbank, but not proven to alter the specificity of the system (Keyhani, 1997). In contrast, a later study claim that mutations making the operon expression high-level constitutive by chbR and nagC mutations are sufficient for the Cel+ phenotype and that no mutations altering substrate specificity are required (Kachroo, 2007).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.