basR:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''basR''  
''basR''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK4106, b4113, JW4074, pmrA''<ref name='LIB:Riley_2006'/>
''ECK4106, b4113, JW4074, pmrA''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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DNA-binding response regulator in two-component regulatory system with BasS product<ref name='LIB:Riley_2006'/>
DNA-binding response regulator in two-component regulatory system with BasS product<ref name='LIB:Riley_2006'/>
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Response regulator for Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)<ref name='LIB:EcoGene'/>
Response regulator for Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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PmrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
PmrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0000160 two-component signal transduction system (phosphorelay) ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0006355 regulation of transcription, DNA-dependent ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0010041 response to iron(III) ion ([http://www.geneontology.org/GO.evidence.shtml IMP,IEP])
'''Molecular Function'''
* GO:0016563 transcription activator activity ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:basRS|basRS]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:basRS|basRS]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=basR&loc=MG1655:4331973..4331305,W3110:4338628..4337960,DH10B:4432335..4431667,REL606:4312664..4311996 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4312664&end=4311996&gene=basR&aa=mkiliveddtlllqglilaaqtegyacdsvttarmaeqsleaghyslvvldlglpdedglhflarirqkkytlpvliltardtltdkiagldvgaddylvkpfaleelharirallrrhnnqgeselivgnltlnmgrrqvwmggeeliltpkeyallsrlmlkagspvhreilyndiynwdnepstntlevhihnlrdkvgkarirtvrgfgymlvaneen Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=basR+AND+escherichia+coli Pubmed(basR)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=basR Textpresso(basR)]


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Revision as of 00:09, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

basR

Gene Synonym(s)

ECK4106, b4113, JW4074, pmrA[1]

Product Desc.

DNA-binding response regulator in two-component regulatory system with BasS product[1]

Response regulator for Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)[2]

Product Synonyms(s)

PmrA[3][1], B4113[3][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): basRS[3]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(basR)    Textpresso(basR)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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BasS is the cognate sensor protein of the BasSR two-component system. Constitutive allele basR53 (pmrA53) confers polymyxin B resistance and deoxycholate hypersensitivity. EvgAS regulon. BasSR confers resistance to Fe(III)-mediated killing.The BasSR regulon has been primarily characterized in Salmonella; unlike E. coli, Salmonella also activates PmrAB(BasSR) in low Mg(2+), mediated by PhoPQ and the PmrD protein.[2]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
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