argK:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''argK'' | ''argK'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK2914, b2918, JW2885, ygfD''<ref name='LIB:Riley_2006'/> | ''ECK2914, b2918, JW2885, ygfD''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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arginine transport ATPase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | arginine transport ATPase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
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Required to convert succinate to propionate, Arg transport?; reported to have ATPase and protein kinase activity<ref name='LIB:EcoGene'/> | Required to convert succinate to propionate, Arg transport?; reported to have ATPase and protein kinase activity<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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membrane ATPase/protein kinase<ref name='LIB:Riley_2006'/>, B2918<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgfD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ArgK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | membrane ATPase/protein kinase<ref name='LIB:Riley_2006'/>, B2918<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgfD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ArgK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0003924 GTPase activity ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IDA]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:scpA-argK-ygfGH|scpA-argK-ygfGH]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:scpA-argK-ygfGH|scpA-argK-ygfGH]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=argK&loc=MG1655:3061009..3062004,W3110:3061643..3062638,DH10B:3154879..3155874,REL606:2948738..2949733 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2948738&end=2949733&gene=argK&aa=mineatlaesirrlrqgeratlaqamtlvesrhprhqalstqlldaimpycgntlrlgvtgtpgagkstfleafgmllireglkvaviavdpsspvtggsilgdktrmndlaraeaafirpvpssghlggasqrarelmllceaagydvvivetvgvgqsetevarmvdcfislqiagggddlqgikkglmevadlivinkddgdnhtnvaiarhmyesalhilrrkydewqprvltcsalekrgideiwhaiidfktaltasgrlqqvrqqqsvewlrkqteeevlnhlfanedfdryyrqtllavknntlsprtglrqlsefiqtqyfd Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=argK+AND+escherichia+coli Pubmed(argK)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=argK Textpresso(argK)] | |||
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Revision as of 00:11, 22 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
argK |
|---|---|
| Gene Synonym(s) |
ECK2914, b2918, JW2885, ygfD[1] |
| Product Desc. |
arginine transport ATPase[2][3] Required to convert succinate to propionate, Arg transport?; reported to have ATPase and protein kinase activity[4] |
| Product Synonyms(s) |
membrane ATPase/protein kinase[1], B2918[2][1], YgfD[2][1], ArgK[2][1] |
| Function from GO |
Molecular Function
|
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): scpA-argK-ygfGH[2] |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
The role of ArgK in arginine transport needs to be reexamined. Characterization of the ArgK ortholog MeaB strongly suggests that ArgK is actually involved in protecting Mcm from inactivation and that ArgK may bind to Mcm. MeaB and Mcm are fused in some organisms. MeaB of M. extorquens binds and hydrolyzes GTP. ArgK is a homolog of the human disease gene MMAA, implicated in methylmalonic aciduria. Part of a four gene operon encoding enzymes converting succinate to propionate. ATPase, but not protein kinase, activity is reportedly required for arginine transport. ArgK does not have predicted transmembrane segments typical of a membrane protein.[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.