sucB:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''sucB''  
''sucB''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0715, b0727, JW0716, lys, met''<ref name='LIB:Riley_2006'/>
''ECK0715, b0727, JW0716, lys, met''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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SucB-lipoate<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
SucB-lipoate<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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2-oxoglutarate dehydrogenase, E2 component; dihydrolipoamide succinyltransferase; acid-inducible; yields succinyl-CoA and CO(2)<ref name='LIB:EcoGene'/>
2-oxoglutarate dehydrogenase, E2 component; dihydrolipoamide succinyltransferase; acid-inducible; yields succinyl-CoA and CO(2)<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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dihydrolipoyl transsuccinase<ref name='LIB:Riley_2006'/>, B0727<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
dihydrolipoyl transsuccinase<ref name='LIB:Riley_2006'/>, B0727<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  


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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:sdhCDAB-sucABCD|sdhCDAB-sucABCD]]<ref name='LIB:EcoCyc10.6'/>, OP00142, sdhCDAB, [[:Category:Txn_unit:sucABCD|sucABCD]]<ref name='LIB:EcoCyc10.6'/>, OP00143, suc  
transcription unit(s): [[:Category:Txn_unit:sdhCDAB-sucABCD|sdhCDAB-sucABCD]]<ref name='LIB:EcoCyc10.6'/>, OP00142, sdhCDAB, [[:Category:Txn_unit:sucABCD|sucABCD]]<ref name='LIB:EcoCyc10.6'/>, OP00143, suc  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 00:49, 10 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

sucB

Gene Synonym(s)

ECK0715, b0727, JW0716, lys, met[1]

Product Desc.

SucB-lipoate[2][3]

SucB-S-succinyldihydrolipoate

2-oxoglutarate dehydrogenase, E2 component; dihydrolipoamide succinyltransferase; acid-inducible; yields succinyl-CoA and CO(2)[4]

Product Synonyms(s)

dihydrolipoyl transsuccinase[1], B0727[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): sdhCDAB-sucABCD[2], OP00142, sdhCDAB, sucABCD[2], OP00143, suc

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


sucAB is a synthetic lethal with sucCD. Residues 104-153 is the E3(Lpd) component binding domain, called the peripheral subunit binding domain (PSBD). When the isolated 50 aa PSBD domain is produced as a protein it is called BBL, which is structuerd at low temperature and may be an example of a downhill protein folding (Packman, 1986; Garcia-Mira, 2002). This controversial topic, centered around experiments with a naphthyl-alanine derivative of BBL termed Naf-BBL, has a topic page with additional citations.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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