ybaZ:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''ybaZ''  
''ybaZ''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0448, b0454, JW0444''<ref name='LIB:Riley_2006'/>
''ECK0448, b0454, JW0444''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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putative methyltransferase<ref name='LIB:EcoCyc10.6'/>; predicted methyltransferase<ref name='LIB:EcoCyc11.1'/>
putative methyltransferase<ref name='LIB:EcoCyc10.6'/>; predicted methyltransferase<ref name='LIB:EcoCyc11.1'/>
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Binds DNA with O(6)-meG or an abasic site; physiological role unknown<ref name='LIB:EcoGene'/>
Binds DNA with O(6)-meG or an abasic site; physiological role unknown<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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predicted methyltransferase<ref name='LIB:Riley_2006'/>, YbaZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B0454<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
predicted methyltransferase<ref name='LIB:Riley_2006'/>, YbaZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B0454<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ybaZ|ybaZ]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ybaZ|ybaZ]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 01:23, 10 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ybaZ

Gene Synonym(s)

ECK0448, b0454, JW0444[1]

Product Desc.

putative methyltransferase[2]; predicted methyltransferase[3]

Binds DNA with O(6)-meG or an abasic site; physiological role unknown[4]

Product Synonyms(s)

predicted methyltransferase[1], YbaZ[2][1], B0454[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ybaZ[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


YbaZ is homologous to methylated-DNA--protein-cysteine methyltransferases Ada and Ogt, but lacks the active site cysteine. YbaZ binds O(6)-alkylguanine residues in DNA and blocks alkyltransferase action; YbaZ does not remove methyl groups from O(6)-methylguanine-containing DNA nor does it have glycosylase or endonuclease activity (Margison, 2007). YbaZ preferentially binds DNA with an abasic site, has base-flipping activity, and binds HelD (Chen, 2008).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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