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Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.<ref name='LIB:EcoGene'/>
Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.<ref name='LIB:EcoGene'/>
Similar to yeast proteins involved in ribosomal function and assembly.






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==References==
==References==
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Revision as of 20:07, 5 August 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

uup

Gene Synonym(s)

ECK0940, b0949, JW0932, ycbH, ycbI, tex[1][2]

Product Desc.

ATP-binding protein with possible role in replication[2][3]

DNA-binding ATPase involved in replication; cytosolic; mutant displays an increased frequency of precise excision of transposons and defective growth of bacteriophage Mu[4]

Product Synonyms(s)

fused predicted transporter subunits of ABC superfamily: ATP-binding components[1], B0949[2][1], YcbH[2][1], YcbI[2][1], Uup[2][1], Tex[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rlmL-uup[2]

Regulation/Activity


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Notes

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Has two ABC ATPase domains; ATPase activity is essential for function. A C-terminal domain of the protein displays predicted structural homology with the Little Finger domain of Y family DNA polymerases and is involved in DNA binding.[4]

Similar to yeast proteins involved in ribosomal function and assembly.





References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.