bamE:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''smpA''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2613, b2617, JW2598, smqA, bamE ''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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SmpA small membrane protein A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:Outer Membrane Protein Assembly Complex|Outer Membrane Protein Assembly Complex]]<ref name='LIB:EcoCyc11.1'/>
Stabilizes BamABCD OM biogenesis complex; member of a BamABCDSmpA multiprotein complex; probable lipoprotein, Cys conserved<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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small membrane lipoprotein<ref name='LIB:Riley_2006'/>, B2617<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SmqA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SmpA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BamE <ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:smpA|smpA]]<ref name='LIB:EcoCyc10.6'/>
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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Revision as of 19:17, 5 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

smpA

Gene Synonym(s)

ECK2613, b2617, JW2598, smqA, bamE [1][2]

Product Desc.

SmpA small membrane protein A[3][4] Component of Outer Membrane Protein Assembly Complex[4]

Stabilizes BamABCD OM biogenesis complex; member of a BamABCDSmpA multiprotein complex; probable lipoprotein, Cys conserved[2]

Product Synonyms(s)

small membrane lipoprotein[1], B2617[3][1], SmqA[3][1], SmpA[3][1], BamE [2]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): smpA[3]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

A consensus has been reached for renaming the genes that encode components of the outer membrane β-barrel assembly machine, (formerly known as the YaeT complex of E. coli or the Omp85 complex of N. meningitidis). The new designation for this multi-component structure is the Bam complex (for beta-barrel assembly machine).

The Bam complex in E. coli consists of BamA (YaeT), BamB (YfgL), BamC (NlpB), BamD (YfiO), and BamE (SmpA). Letters have been assigned on the basis of molecular weight, from highest to lowest [2].

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smpA mutants are sensitive to rifampin, cholate, and SDS/EDTA, indicating an OM defect (Sklar, 2007). smpA bamB double mutant is non-viable (Sklar, 2007). SmpA is homologous to P. aeruginosa OmlA. First 19 aa are predicted to be a type II signal peptide.[2]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7