seqA:Quickview: Difference between revisions
imported>Wikientrybot No edit summary |
imported>Wikientrybot No edit summary |
||
| Line 28: | Line 28: | ||
|- | |- | ||
!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
|| | |||
''seqA'' | |||
|- | |- | ||
!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
|| | |||
''ECK0675, b0687, JW0674''<ref name='LIB:Riley_2006'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
|| | |||
SeqA, negative modulator of initiation of replication<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | |||
Sequesters newly replicated hemimethylated oriC origins to prevent re-initiation; binds hemimethylated GATC sequences; SeqA foci required for chromosome segregation; binds and stimulates Topo IV<ref name='LIB:EcoGene'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
|| | |||
regulatory protein for replication initiation<ref name='LIB:Riley_2006'/>, B0687<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SeqA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
|| | |||
|- | |- | ||
!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
|| | |||
transcription unit(s): [[:Category:Txn_unit:seqA-pgm|seqA-pgm]]<ref name='LIB:EcoCyc10.6'/> | |||
|- | |- | ||
!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
|| | |||
|-class='sortbottom' | |-class='sortbottom' | ||
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.3113.S49b024ecd855a&page=3113&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] | |[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.3113.S49b024ecd855a&page=3113&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table] || | ||
|} | |} | ||
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.3113.S49b024ecd855a--></protect> | <!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.3113.S49b024ecd855a--></protect> | ||
Revision as of 19:15, 5 March 2009
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
seqA |
|---|---|
| Gene Synonym(s) |
ECK0675, b0687, JW0674[1] |
| Product Desc. |
SeqA, negative modulator of initiation of replication[2][3] Sequesters newly replicated hemimethylated oriC origins to prevent re-initiation; binds hemimethylated GATC sequences; SeqA foci required for chromosome segregation; binds and stimulates Topo IV[4] |
| Product Synonyms(s) |
regulatory protein for replication initiation[1], B0687[2][1], SeqA[2][1] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
SeqA is required for the membrane binding of hemimethylated oriC in vitro. SeqA may facilitate cII binding to phage lambda promoters, enhancing transcription. SeqA self-association function is in the N-terminal domain. DNA-binding activity is in C-terminal domain. SeqA expression is negatively modulated by HU. SeqA is a homotetramer. aphA(hobH) mutants overproduce SeqA.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.