phoA:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''phoA''  
''phoA''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK0378, b0383, JW0374, psiA''<ref name='LIB:Riley_2006'/>
''ECK0378, b0383, JW0374, psiA''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Alkaline phosphatase, periplasmic; binds Zn(II); dimeric<ref name='LIB:EcoGene'/>
Alkaline phosphatase, periplasmic; binds Zn(II); dimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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bacterial alkaline phosphatase<ref name='LIB:Riley_2006'/>, B0383<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsiA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
bacterial alkaline phosphatase<ref name='LIB:Riley_2006'/>, B0383<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsiA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PhoA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:phoA-psiF|phoA-psiF]]<ref name='LIB:EcoCyc10.6'/>, OP00071, phoA  
transcription unit(s): [[:Category:Txn_unit:phoA-psiF|phoA-psiF]]<ref name='LIB:EcoCyc10.6'/>, OP00071, phoA  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 03:34, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

phoA

Gene Synonym(s)

ECK0378, b0383, JW0374, psiA[1]

Product Desc.

PhoA[2][3];

Component of alkaline phosphatase[2][3]

Alkaline phosphatase, periplasmic; binds Zn(II); dimeric[4]

Product Synonyms(s)

bacterial alkaline phosphatase[1], B0383[2][1], PsiA[2][1], PhoA[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): phoA-psiF[2], OP00071, phoA

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Arg22 is removed from the mature enzyme by Iap to form isozyme 3. Isozyme 2 is a heterodimer of isozymes 1 and 3 subunits. PhoA requires the reducing environment of the periplasm and DsbA for activity; cysteine bonds C190-C200 and C308-C358 are needed. PhoA fusions are used to indicate periplasmic location of hybrid proteins.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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