malT:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''malT''  
''malT''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK3405, b3418, JW3381, malA''<ref name='LIB:Riley_2006'/>
''ECK3405, b3418, JW3381, malA''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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MalT transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
MalT transcriptional activator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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ATP-dependent transcriptional activator for the mal regulon<ref name='LIB:EcoGene'/>
ATP-dependent transcriptional activator for the mal regulon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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fused conserved protein<ref name='LIB:Riley_2006'/>, DNA-binding transcriptional activator, maltotriose-ATP-binding<ref name='LIB:Riley_2006'/>, MalA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3418<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
fused conserved protein<ref name='LIB:Riley_2006'/>, DNA-binding transcriptional activator, maltotriose-ATP-binding<ref name='LIB:Riley_2006'/>, MalA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B3418<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:malT|malT]]<ref name='LIB:EcoCyc10.6'/>, OP00128  
transcription unit(s): [[:Category:Txn_unit:malT|malT]]<ref name='LIB:EcoCyc10.6'/>, OP00128  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 02:03, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

malT

Gene Synonym(s)

ECK3405, b3418, JW3381, malA[1]

Product Desc.

MalT transcriptional activator[2][3]

ATP-dependent transcriptional activator for the mal regulon[4]

Product Synonyms(s)

fused conserved protein[1], DNA-binding transcriptional activator, maltotriose-ATP-binding[1], MalA[2][1], B3418[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): malT[2], OP00128

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Activated by maltotriose and ATP to form active oligomers. Signal transduction ATPases with numerous domains (STAND) protein. ATP hydrolysis is not required for transcription activation (Richet, 1989), but is required to recycle back to the inactive form, which has ADP, not ATP bound (Marquenet, 2007). MalY (Clausen, 2000; Schreiber, 2000), MalK (Reyes, 1988; Panagiotidis, 1998; Bohm, 2002) and Aes (Joly, 2002) negatively regulate MalT activity by binding and blocking maltotriose activation. MalT is required for phage lambda sensitivity.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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