fis:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Standard Name
!align=left |Standard Name
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''fis''  
''fis''  
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left |Gene Synonym(s)
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''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/>
''ECK3248, b3261, JW3229, nbp''<ref name='LIB:Riley_2006'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left |Product Desc.
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Fis transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Fis transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric<ref name='LIB:EcoGene'/>
Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left |Product Synonyms(s)
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global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
global DNA-binding transcriptional dual regulator<ref name='LIB:Riley_2006'/>, B3261<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Nbp<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fis<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:dusB-fis|dusB-fis]]<ref name='LIB:EcoCyc10.6'/>, OP00028, fis, yhdG-fis  
transcription unit(s): [[:Category:Txn_unit:dusB-fis|dusB-fis]]<ref name='LIB:EcoCyc10.6'/>, OP00028, fis, yhdG-fis  
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left |Regulation/Activity
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Revision as of 01:05, 9 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

fis

Gene Synonym(s)

ECK3248, b3261, JW3229, nbp[1]

Product Desc.

Fis transcriptional dual regulator[2][3]

Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric[4]

Product Synonyms(s)

global DNA-binding transcriptional dual regulator[1], B3261[2][1], Nbp[2][1], Fis[2][1], site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription[2][1]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): dusB-fis[2], OP00028, fis, yhdG-fis

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


fis transcription is supercoiling-dependent. Overexpression causes filamentous biofilm formation. Decreased levels of Fis inhibit open complex formation, inhibiting oriC unwinding by blocking IHF and DnaA low affinity binding sites. Polyamine modulon. Mutations affect chromosomal supercoliing.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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