fis:Quickview: Difference between revisions

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===Notes===
===Notes===
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fis transcription is supercoiling-dependent.  Overexpression causes filamentous biofilm formation.  Decreased levels of Fis inhibit open complex formation, inhibiting oriC unwinding by blocking IHF and DnaA low affinity binding sites. Polyamine modulon. Mutations affect chromosomal supercoliing.<ref name='LIB:EcoGene'/>





Revision as of 23:47, 2 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

fis (synonyms: ECK3248, b3261, JW3229, nbp)[1]

Product(s)

Fis product[1]: global DNA-binding transcriptional dual regulator product, B3261 product, Nbp product, site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription product

Description

Fis transcriptional dual regulator[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): dusB-fis[2], OP00028, fis, yhdG-fis

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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fis transcription is supercoiling-dependent. Overexpression causes filamentous biofilm formation. Decreased levels of Fis inhibit open complex formation, inhibiting oriC unwinding by blocking IHF and DnaA low affinity binding sites. Polyamine modulon. Mutations affect chromosomal supercoliing.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.