plsX:Quickview: Difference between revisions
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PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProt: Q97TA6) (Lu, 2006). ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.<ref name='LIB:EcoGene'/> | |||
Revision as of 01:12, 3 March 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
PlsX product[1]: fatty acid/phospholipid synthesis protein product, B1090 product |
| Description | |
| Knock-Out Phenotype | |
| Regulation/Expression |
transcription unit(s): plsX-fabHDG[2], rpmF-plsX-fabHDG[2] |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProt: Q97TA6) (Lu, 2006). ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.