birA:Quickview: Difference between revisions

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===Notes===
===Notes===
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Biotinyl-5'-AMP is the co-repressor and is also synthesized by BirA (Cronan, 1988). BirA biotinylates AccB on K122. The biotin operon is regulated by the rate of protein biotination (Cronan, 1989).<ref name='LIB:EcoGene'/>





Revision as of 23:31, 2 March 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

birA (synonyms: ECK3965, b3973, JW3941, bioR, dhbB)[1]

Product(s)

BirA product[1]: bifunctional biotin-[acetylCoA carboxylase] holoenzyme synthetase and DNA-binding transcriptional repressor, bio-5'-AMP-binding product, B3973 product, BioR product, DhbB product, biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor product, biotin ligase product, BirA transcriptional repressor product

Description

BIOTINLIG-MONOMER[2] BirA transcriptional repressor, biotin-[acetyl-CoA-carboxylase] ligase[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): murB[2]

Regulation/Activity


edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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Biotinyl-5'-AMP is the co-repressor and is also synthesized by BirA (Cronan, 1988). BirA biotinylates AccB on K122. The biotin operon is regulated by the rate of protein biotination (Cronan, 1989).[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.