folE:Quickview: Difference between revisions
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Although a folE null mutant could not be made by Baba (2006), leading to its inclusion in the set of 303 essential genes, Klaus (2005) were able to construct a deletion mutation in folE. It requires LB+ thymidine and grows poorly, explaining the Baba negative result. Thus, folE is not an essential gene. FolE is the first enzyme of pre-Q(0) biosynthesis (Phillips, 2008).<ref name='LIB:EcoGene'/> | |||
Revision as of 01:07, 3 March 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
FolE product[1]: GTP cyclohydrolase I product, B2153 product |
| Description |
GTP cyclohydrolase I monomer[2][3] Component of GTP cyclohydrolase I[2] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Although a folE null mutant could not be made by Baba (2006), leading to its inclusion in the set of 303 essential genes, Klaus (2005) were able to construct a deletion mutation in folE. It requires LB+ thymidine and grows poorly, explaining the Baba negative result. Thus, folE is not an essential gene. FolE is the first enzyme of pre-Q(0) biosynthesis (Phillips, 2008).[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.