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Arg22 is removed from the mature enzyme by Iap to form isozyme 3. Isozyme 2 is a heterodimer of isozymes 1 and 3 subunits. PhoA requires the reducing environment of the periplasm and DsbA for activity; cysteine bonds C190-C200 and C308-C358 are needed. PhoA fusions are used to indicate periplasmic location of hybrid proteins.<ref name='LIB:EcoGene'/> | |||
Revision as of 00:21, 3 March 2009
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name | |
|---|---|
| Product(s) |
PhoA product[1]: bacterial alkaline phosphatase product, B0383 product, PsiA product |
| Description |
Component of alkaline phosphatase[2] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Arg22 is removed from the mature enzyme by Iap to form isozyme 3. Isozyme 2 is a heterodimer of isozymes 1 and 3 subunits. PhoA requires the reducing environment of the periplasm and DsbA for activity; cysteine bonds C190-C200 and C308-C358 are needed. PhoA fusions are used to indicate periplasmic location of hybrid proteins.[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.