Genes not mapped to a genome sequence: Difference between revisions

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|- align='left' bgcolor='#CCCCFF'
!|Gene!!Approx. Map Location!!Mnemonic!!Notes
!|Gene!!Approx. Map Location!!Mnemonic!!Notes
|-
|
abpS
|
63.5
|
Arg binding protein
|
Low-affinity transport system for arginine and ornithine; periplasmic binding protein [[cgsc_site:18562|CGSC]]
|-
|
abs
|
94.1
|
Antibiotic sensitivity
|
Sensitivity and permeability to antibiotics and dyes [[cgsc_site:18559|CGSC]]
|-
|
acpX
|
43.9
|
Acyl carrier protein
|
acpS; originally thought to be holo-ACP synthase; perhaps cryptic second gene or regulator [[cgsc_site:1046|CGSC]]
|-
|
acrC
|
4.5
|
Acridine
|
Sensitivity to acriflavine; transmembrane protein [[cgsc_site:1044|CGSC]]
|-
|
adhB
|
19.1
|
Alcohol dehydrogenase
|
Alcohol dehydrogenase [[cgsc_site:36932|CGSC]]
|-
|
aga
|
70.7
|
Acetylgalactosamine
|
Cluster of putative N-acetylgalactosamine pathway genes, including the kba gene, and mannose permease homologs [[cgsc_site:55305|CGSC]]
|-
|
aroI
|
84.2
|
Aromatic
|
Function unknown [[cgsc_site:1000|CGSC]]
|-
|
att
|
17.3
|
Attachment
|
att92, att434; lambda attachment site [[cgsc_site:980|CGSC]]
|-
|
azaA
|
44.6
|
Azaserine
|
Mutants azaserine resistant [[cgsc_site:970|CGSC]]
|-
|
azaB
|
71.9
|
Azaserine
|
Mutants azaserine resistant [[cgsc_site:969|CGSC]]
|-
|
azl
|
58.1
|
Azaleucine
|
Mutants azaleucine resistant; regulates ilv and leu [[cgsc_site:967|CGSC]]
|-
|
bfm
|
85.9
|
BF23 multiplication
|
Controls phage BF23 multiplication [[cgsc_site:966|CGSC]]
|-
|
bglT
|
84.9
|
-Glucoside
|
bglE; regulatory gene for BglA [[cgsc_site:961|CGSC]]
|-
|
bioP
|
86.6
|
Biotin
|
bir, birB; biotin transport [[cgsc_site:953|CGSC]]
|-
|
brnR
|
8.5
|
Branched chain
|
Mutants valine resistant, glycylvaline sensitive [[cgsc_site:949|CGSC]]
|-
|
brnS
|
1.2
|
Branched chain
|
Mutants valine resistant, glycylvaline sensitive [[cgsc_site:948|CGSC]]
|-
|
brnT
|
65.2
|
Branched chain
|
Low-affinity transport of Ile [[cgsc_site:947|CGSC]]
|-
|
bymA
|
93.2
|
Bypass maltose
|
Growth on maltose in MalT cells [[cgsc_site:944|CGSC]]
|-
|
calA
|
95.0
|
Calcium
|
Calcium-proton antiport activity [[cgsc_site:941|CGSC]]
|-
|
calC
|
15.2
|
Calcium
|
Calcium transport; mutants defective in chemotaxis [[cgsc_site:940|CGSC]]
|-
|
calD
|
9.4
|
Calcium
|
Calcium transport; mutants defective in chemotaxis [[cgsc_site:939|CGSC]]
|-
|
cdsS
|
71.7
|
CDP diglyceride synthase
|
Stability of CDP diglyceride synthase [[cgsc_site:18490|CGSC]]
|-
|
cpsA
|
45.4
|
Capsular polysaccharide synthesis
|
Colanic acid (CPS) biosynthesis [[cgsc_site:18463|CGSC]]
|-
|
cpsC
|
45.8
|
Capsular polysaccharide synthesis
|
Colanic acid (CPS) biosynthesis [[cgsc_site:18457|CGSC]]
|-
|
cpsD
|
45.8
|
Capsular polysaccharide synthesis
|
Colanic acid (CPS) biosynthesis [[cgsc_site:18454|CGSC]]
|-
|
cpsE
|
45.8
|
Capsular polysaccharide synthesis
|
Colanic acid (CPS) biosynthesis [[cgsc_site:51241|CGSC]]
|-
|
cpsF
|
90.2
|
Capsular polysaccharide synthesis
|
Colanic acid (CPS) biosynthesis [[cgsc_site:18448|CGSC]]
|-
|
cpxB
|
41.3
|
Conjugative plasmid expression
|
Phage Q resistance, membrane protein [[cgsc_site:907|CGSC]]
|-
|
crg
|
28.8
|
Cold resistant growth
|
Allows cold-resistant growth [[cgsc_site:18445|CGSC]]
|-
|
csiA
|
85.3
|
Carbon starvation induced
|
Stationary phase inducible protein [[cgsc_site:36892|CGSC]]
|-
|
csiB
|
17.4
|
Carbon starvation induced
|
Stationary phase inducible protein [[cgsc_site:36895|CGSC]]
|-
|
csiC
|
66.0
|
Carbon starvation induced
|
Stationary phase inducible protein [[cgsc_site:36898|CGSC]]
|-
|
csiF
|
8.6
|
Carbon starvation induced
|
Stationary phase inducible protein [[cgsc_site:36998|CGSC]]
|-
|
cup
|
97.0
|
Carbohydrate uptake
|
Mutants have defective carbohydrate uptake [[cgsc_site:18442|CGSC]]
|-
|
cxm
|
6.3
|
Carbon-xylose metabolism
|
cxr; methyl glyoxal synthesis; D-xylose utilization [[cgsc_site:903|CGSC]]
|-
|
cysX
|
81.5
|
Cysteine
|
Reading frame in opposite orientation within cysE gene; polypeptide synthesized in maxicells [[cgsc_site:55332|CGSC]]
|-
|
dadQ
|
98.9
|
D-Amino acid dehydrogenase
|
alnR; regulator of dad regulon [[cgsc_site:882|CGSC]]
|-
|
dctB
|
16.4
|
Dicarboxylic acid transport
|
Uptake of C-4 dicarboxylic acids; 3-fluoromalate resistance, D-tartrate resistant [[cgsc_site:871|CGSC]]
|-
|
del
|
64.3
|
Deletion
|
Affects frequency of IS1-mediated deletions; 1,000-fold reduction in deletion frequency [[cgsc_site:869|CGSC]]
|-
|
dgkR
|
93.7
|
Diglyceride kinase
|
Regulatory [[cgsc_site:861|CGSC]]
|-
|
dif
|
34.2
|
Deletion-induced filamentation
|
Recombination site in terminus, recA independent [[cgsc_site:30208|CGSC]]
|-
|
dinY
|
41.9
|
Damage inducible
|
Repair gene [[cgsc_site:36880|CGSC]]
|-
|
dnaI
|
40.3
|
DNA
|
DNA biosynthesis [[cgsc_site:846|CGSC]]
|-
|
dppG
|
14.0
|
Dipeptide permease
|
Uptake of dipeptides; dipeptide permease [[cgsc_site:835|CGSC]]
|-
|
dvl
|
7.4
|
Dye-visible light?
|
Sensitivity to SDS and toluidine blue plus light [[cgsc_site:18418|CGSC]]
|-
|
ebgB
|
69.5
|
Evolved -galactosidase
|
Cryptic -galactoside utilization, possible paralog of lacY [[cgsc_site:18415|CGSC]]
|-
|
envN
|
4.2
|
Envelope
|
Affects envelope; defects osmotically remedied [[cgsc_site:811|CGSC]]
|-
|
envP
|
90.4
|
Envelope
|
Affects envelope; defects osmotically remedied [[cgsc_site:810|CGSC]]
|-
|
envQ
|
60.7
|
Envelope
|
Affects envelope; defects osmotically remedied [[cgsc_site:809|CGSC]]
|-
|
envT
|
14.2
|
Envelope
|
Affects envelope; defects osmotically remedied [[cgsc_site:808|CGSC]]
|-
|
epp
|
|
E-pentapeptide
|
Minigene within 23S rRNA encoding functional pentapeptide; erythromycin resistance [[cgsc_site:51135|CGSC]]
|-
|
esp
|
17.3
|
Efficiency site for phage
|
Site for efficient packaging of phage T1 [[cgsc_site:805|CGSC]]
|-
|
exbC
|
61.5
|
Export
|
Uptake of enterochelin; resistance or sensitivity to colicins [[cgsc_site:803|CGSC]]
|-
|
expA
|
22.2
|
Export
|
Expression of a group of export proteins [[cgsc_site:802|CGSC]]
|-
|
fatA
|
71.7
|
Fatty acid
|
Utilization of trans unsaturated fatty acids [[cgsc_site:18403|CGSC]]
|-
|
fcsA
|
86.9
|
Filamentous, cold sensitive
|
Cold-sensitive cell division mutant [[cgsc_site:787|CGSC]]
|-
|
fexB
|
86.7
|
F exclusion
|
Affects ArcA phenotype [[cgsc_site:778|CGSC]]
|-
|
fhlB
|
95.1
|
Formate hydrogen-lyase
|
Formate hydrogen-lyase; activated by fhlA [[cgsc_site:36851|CGSC]]
|-
|
fipB
|
86.0
|
F1 phage
|
Morphogenesis of phage F1 [[cgsc_site:18334|CGSC]]
|-
|
fipC
|
75.0
|
F1 phage
|
Morphogenesis of phage F1 [[cgsc_site:18331|CGSC]]
|-
|
flkB
|
95.4
|
FKBP-like
|
Periplasmic PPIase, of FK506-binding protein type (EC 5.2.1.8); contains pipecolic acid residue [[cgsc_site:48137|CGSC]]
|-
|
gadR
|
79.6
|
Glutamate deCase
|
Regulatory gene for gat? [[cgsc_site:726|CGSC]]
|-
|
garA
|
15.8
|
Glucarate
|
D-Glucarate utilization [[cgsc_site:717|CGSC]]
|-
|
garB
|
3.6
|
Glucarate
|
D-Glucarate utilization [[cgsc_site:716|CGSC]]
|-
|
glmX
|
26.2
|
Glucosamine
|
Affects suppression of glmS mutations by nagB [[cgsc_site:36538|CGSC]]
|-
|
gltE
|
81.4
|
Glutamate
|
Glutamyl-tRNA synthetase; possible regulatory subunit [[cgsc_site:685|CGSC]]
|-
|
gltH
|
21.8
|
Glutamate
|
Growth on glutamate [[cgsc_site:684|CGSC]]
|-
|
gltR
|
92.3
|
Glutamate
|
Growth on glutamate at 42C [[cgsc_site:682|CGSC]]
|-
|
gprA
|
0.3
|
Growth of phage, replication
|
Replication of certain lambdoid phage [[cgsc_site:15896|CGSC]]
|-
|
gprB
|
0.2
|
Growth of phage, replication
|
Replication of certain lambdoid phage [[cgsc_site:15890|CGSC]]
|-
|
gurC
|
18.0
|
Glucuronide
|
Utilization of glucuronides [[cgsc_site:653|CGSC]]
|-
|
het
|
84.6
|
Heterogeneous size
|
cop; possibly structural gene for DNA-binding protein; near ori [[cgsc_site:640|CGSC]]
|-
|
hslC
|
19.9
|
Heat shock locus
|
Protein expressed as heat shock regulon member [[cgsc_site:36762|CGSC]]
|-
|
hslD
|
24.1
|
Heat shock locus
|
Protein expressed as heat shock regulon member [[cgsc_site:36765|CGSC]]
|-
|
hslK
|
40.7
|
Heat shock locus
|
Protein expressed as heat shock regulon member [[cgsc_site:36945|CGSC]]
|-
|
hslW
|
94.2
|
Heat shock locus
|
Heat-inducible; regulatory gene, near groE [[cgsc_site:41190|CGSC]]
|-
|
ilvF
|
57.0
|
Isoleucine-valine (requirement)
|
Production of valine-resistant acetolactate synthase activity [[cgsc_site:604|CGSC]]
|-
|
ilvR
|
99.9
|
Isoleucine-valine
|
[[cgsc_site:15917|CGSC]]
|-
|
ilvU
|
6.4
|
Isoleucine-valine (requirement)
|
Regulation of ileS and modification of Ile tRNA2 and Val tRNA2 [[cgsc_site:599|CGSC]]
|-
|
inm
|
79.0
|
Insensitive NG mutagenesis
|
Susceptibility to mutagenesis by nitrosoguanidine [[cgsc_site:595|CGSC]]
|-
|
isfA
|
86.0
|
Inhibits SOS function
|
Regulatory gene; SOS-related [[cgsc_site:41044|CGSC]]
|-
|
ksgB
|
37.7
|
Kasugamycin
|
High-level resistance to kasugamycin [[cgsc_site:582|CGSC]]
|-
|
ksgC
|
12.0
|
Kasugamycin
|
Resistance to kasugamycin; affects ribosomal protein S2 [[cgsc_site:581|CGSC]]
|-
|
ksgD
|
30.9
|
Kasugamycin
|
Resistance to kasugamycin [[cgsc_site:580|CGSC]]
|-
|
leuJ
|
13.7
|
Leucine (biosynthesis)
|
flr; regulation of leu and ilv operons [[cgsc_site:18196|CGSC]]
|-
|
leuR
|
79.3
|
Leucine
|
Regulates level of leucyl-tRNA synthetase [[cgsc_site:567|CGSC]]
|-
|
leuY
|
9.5
|
Leucine
|
Regulates level of leucyl-tRNA synthetase [[cgsc_site:560|CGSC]]
|-
|
lev
|
9.0
|
Levallorphan
|
Resistance to levallorphan [[cgsc_site:559|CGSC]]
|-
|
linB
|
29.3
|
Lincomycin
|
High-level lincomycin resistance [[cgsc_site:556|CGSC]]
|-
|
lpcB
|
68.0
|
Lipopolysaccharide core
|
mrc, pon; T-phage resistance, novobiocin sensitivity [[cgsc_site:545|CGSC]]
|-
|
lrb
|
7.3
|
L-Ribose (utilization)
|
Affects NADPH-linked L-ribose reductase activity [[cgsc_site:36791|CGSC]]
|-
|
lysX
|
63.3
|
Lysine
|
Lysine excretion [[cgsc_site:536|CGSC]]
|-
|
lytA
|
60.6
|
Lytic
|
Tolerance to -lactams; autolysis [[cgsc_site:18184|CGSC]]
|-
|
mafA
|
0.9
|
Maintenance of F
|
Maintenance of F-like plasmids [[cgsc_site:534|CGSC]]
|-
|
mafB
|
1.9
|
Maintenance of F
|
Maintenance of F-like plasmids [[cgsc_site:533|CGSC]]
|-
|
mbrB
|
88.6
|
Mothball resistant
|
Resistance to camphor vapors; coupling of cell division and replication, growth rate and partitioning [[cgsc_site:36929|CGSC]]
|-
|
meb
|
78.7
|
malE bypass
|
Suppressor of malE secB-defective transport of mal-binding protein [[cgsc_site:28194|CGSC]]
|-
|
mglR
|
16.9
|
Methyl-galactoside
|
R-MG; regulatory gene [[cgsc_site:498|CGSC]]
|-
|
mms
|
69.2
|
Macromolecular synthesis
|
Complex operon, macromolecular synthesis [[cgsc_site:36863|CGSC]]
|-
|
mng
|
40.0
|
Manganese
|
Manganese resistance [[cgsc_site:494|CGSC]]
|-
|
mraA
|
2.0
|
Murein cluster a
|
D-Alanine carboxypeptidase [[cgsc_site:489|CGSC]]
|-
|
mul
|
83.1
|
Mutability lambda
|
Mutability in UV-radiated lambda phage [[cgsc_site:477|CGSC]]
|-
|
murH
|
99.3
|
Murein
|
Terminal stage in peptidoglycan synthesis, incorporating disaccharide peptide units into wall [[cgsc_site:18136|CGSC]]
|-
|
mutG
|
43.7
|
Mutator
|
Mutation causes high C-to-T mutation in second C of CCAGG; near but distinct from vsr; provisionally termed mutG [[cgsc_site:28933|CGSC]]
|-
|
nalB
|
60.2
|
Nalidixic acid
|
Sensitivity to nalidixic acid (NAL) [[cgsc_site:460|CGSC]]
|-
|
neaB
|
75.0
|
Neamine
|
Neamine sensitivity [[cgsc_site:456|CGSC]]
|-
|
nfnA
|
80.8
|
Nitrofurantoin
|
Nitrofurantoin sensitivity [[cgsc_site:18100|CGSC]]
|-
|
nfrD
|
54.2
|
N4 (phage) resistant
|
Phage N4 susceptibility [[cgsc_site:36113|CGSC]]
|-
|
non
|
45.7
|
Nonmucoid
|
Affects capsule formation [[cgsc_site:446|CGSC]]
|-
|
oppE
|
98.9
|
Oligopeptide permease
|
Oligopeptide transport [[cgsc_site:18082|CGSC]]
|-
|
opr
|
19.0
|
rpo reversed
|
Rate of degradation of aberrant RNAP-subunit proteins [[cgsc_site:18079|CGSC]]
|-
|
ops
|
66.1
|
Overproduction of polysaccharide
|
Level of exopolysaccharide production [[cgsc_site:18076|CGSC]]
|-
|
oriJ
|
30.5
|
Origin of replication
|
Locus in defective prophage rac [[cgsc_site:430|CGSC]]
|-
|
pac
|
31.0
|
Phenylacetate
|
Phenylacetate degradation [[cgsc_site:18067|CGSC]]
|-
|
phxB
|
17.0
|
Phage X
|
Adsorption of X154 [[cgsc_site:389|CGSC]]
|-
|
poaR
|
65.9
|
Proline oxidase
|
Regulation of proline oxidase production [[cgsc_site:377|CGSC]]
|-
|
popD
|
0.2
|
Porphyrin
|
5-Aminolevulinate dehydratase (EC 4.2.1.24) [[cgsc_site:371|CGSC]]
|-
|
prlZ
|
71.4
|
Protein localization
|
Suppresses export defects in signal sequence mutations [[cgsc_site:36421|CGSC]]
|-
|
proT
|
83.8
|
Proline
|
Proline transport carrier protein, putative [[cgsc_site:359|CGSC]]
|-
|
pus
|
20.6
|
Reverse of sup (amber)
|
Reverses accentuation effects of amber suppressor on relB mutations [[cgsc_site:334|CGSC]]
|-
|
qin
|
35.1
|
Q independent
|
kim; cryptic lambdoid phage [[cgsc_site:17529|CGSC]]
|-
|
qmeC
|
75.3
|
Q membrane
|
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:321|CGSC]]
|-
|
qmeD
|
64.4
|
Q membrane
|
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:320|CGSC]]
|-
|
qmeE
|
37.9
|
Q membrane
|
Glycine resistance; penicillin sensitivity; membrane defect [[cgsc_site:319|CGSC]]
|-
|
ras
|
9.9
|
Radiation sensitive
|
Sensitive to X rays and UV [[cgsc_site:316|CGSC]]
|-
|
rdgA
|
16.1
|
RecA-dependent growth
|
Dependence of growth upon recA gene product [[cgsc_site:17971|CGSC]]
|-
|
relX
|
62.8
|
Relaxed
|
Control of ppGpp synthesis [[cgsc_site:304|CGSC]]
|-
|
rer
|
89.9
|
Resistance to radiation
|
Resistance to UV and gamma radiation [[cgsc_site:302|CGSC]]
|-
|
ridA
|
73.1
|
Rifampin dependence
|
Rifampin resistance and dependence [[cgsc_site:285|CGSC]]
|-
|
ridB
|
85.5
|
Rifampin dependence
|
Transcription and translation; rifampin (rifamycin) sensitivity [[cgsc_site:17935|CGSC]]
|-
|
rimB
|
38.9
|
Ribosomal modification
|
50S ribosomal subunit maturation [[cgsc_site:284|CGSC]]
|-
|
rimC
|
26.2
|
Ribosomal modification
|
50S ribosomal subunit maturation [[cgsc_site:283|CGSC]]
|-
|
rimD
|
87.7
|
Ribosomal modification
|
50S ribosomal subunit maturation [[cgsc_site:282|CGSC]]
|-
|
rimE
|
74.1
|
Ribosomal modification
|
Ribosomal protein modification [[cgsc_site:281|CGSC]]
|-
|
rimH
|
13.6
|
Ribosomal modification
|
stsB; ribosomal modification [[cgsc_site:278|CGSC]]
|-
|
rit
|
89.2
|
Ribosomal thermolability
|
Affects thermolability of 50S ribosomal subunit [[cgsc_site:274|CGSC]]
|-
|
rorB
|
85.1
|
Roentgen resistance
|
Sensitivity to ionizing radiation, mitomycin C [[cgsc_site:36611|CGSC]]
|-
|
rrnA
|
96.9
|
Ribosomal RNA (operon)
|
See Fig. 1 [[cgsc_site:23593|CGSC]]
|-
|
rrnB
|
89.8
|
Ribosomal RNA (operon)
|
cqsE, rrnB1; see Fig. 1 [[cgsc_site:195|CGSC]]
|-
|
rrnC
|
84.9
|
Ribosomal RNA (operon)
|
cqsB; see Fig. 1 [[cgsc_site:19503|CGSC]]
|-
|
rrnD
|
73.7
|
Ribosomal RNA (operon)
|
cqsD; see Fig. 1 [[cgsc_site:193|CGSC]]
|-
|
rrnE
|
90.7
|
Ribosomal RNA (operon)
|
rrnD1; see Fig. 1 [[cgsc_site:192|CGSC]]
|-
|
rrnG
|
58.7
|
Ribosomal RNA (operon)
|
See Fig. 1 [[cgsc_site:10891|CGSC]]
|-
|
rrnH
|
4.8
|
Ribosomal RNA (operon)
|
See Fig. 1 [[cgsc_site:190|CGSC]]
|-
|
sds
|
30.4
|
Suppresses disulfide bond
|
Motility defects [[cgsc_site:|CGSC]]
|-
|
semA
|
40.5
|
Sensitivity to microcin
|
Sensitivity to microcin E492 [[cgsc_site:17884|CGSC]]
|-
|
serR
|
2.3
|
Serine
|
Regulates level of seryl-tRNA synthetase [[cgsc_site:|CGSC]]
|-
|
sfiC
|
25.8
|
Septum formation inhibition
|
Element of e14, inhibitor of cell division [[cgsc_site:17875|CGSC]]
|-
|
sipC
|
82.6
|
Suppressor of increased permeability
|
Mutations reverse the susceptibility to vancomycin and other hydrophobic antibiotics caused by TraT plasmid gene [[cgsc_site:51306|CGSC]]
|-
|
sipD
|
82.7
|
Suppressor of increased permeability
|
Same phenotype as that produced by sipC [[cgsc_site:36869|CGSC]]
|-
|
sir
|
61.2
|
SOS-independent repair
|
SOS-independent repair of mitomycin C-induced DNA damage [[cgsc_site:36505|CGSC]]
|-
|
sloB
|
75.0
|
Slow growth
|
Tolerance for amidinopenicillin and nalidixic acid; slow growth rate [[cgsc_site:162|CGSC]]
|-
|
slrR
|
60.9
|
Sorbitol
|
gutR; regulatory gene for srl [[cgsc_site:152|CGSC]]
|-
|
srnA
|
9.4
|
Stable RNA
|
Degradation of stable RNA [[cgsc_site:151|CGSC]]
|-
|
ssaE
|
52.5
|
Suppression secA
|
Suppresses secA mutations [[cgsc_site:17869|CGSC]]
|-
|
ssaG
|
41.8
|
Suppression secA
|
Suppresses secA mutations [[cgsc_site:17866|CGSC]]
|-
|
ssaH
|
94.1
|
Suppression secA
|
Suppresses secA mutations [[cgsc_site:17863|CGSC]]
|-
|
ssyD
|
3.0
|
Suppression of secY
|
Suppressor of secY mutation [[cgsc_site:17848|CGSC]]
|-
|
stfZ
|
2.3
|
fts in reverse
|
Antisense RNA blocks ftsZ mRNA translation, inhibits cell division [[cgsc_site:36124|CGSC]]
|-
|
stkA
|
77.5
|
Suppressor of transposase killing
|
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36083|CGSC]]
|-
|
stkB
|
86.1
|
Suppressor of transposase killing
|
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36093|CGSC]]
|-
|
stkC
|
98.5
|
Suppressor of transposase killing
|
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36087|CGSC]]
|-
|
stkD
|
28.6
|
Suppressor of transposase killing
|
Suppresses cell aberrations and death caused by Tn5 transposase overexpression [[cgsc_site:36090|CGSC]]
|-
|
strC
|
7.0
|
Streptomycin
|
strB; low-level streptomycin resistance; modifies ribosome structure [[cgsc_site:149|CGSC]]
|-
|
strM
|
78.3
|
Streptomycin
|
asuF?; control of ribosomal ambiguity [[cgsc_site:148|CGSC]]
|-
|
stsA
|
84.7
|
|
Altered RNase activity [[cgsc_site:147|CGSC]]
|-
|
suhA
|
78.4
|
Suppressor heat-shock proteins
|
Induction of heat shock genes [[cgsc_site:17839|CGSC]]
|-
|
sup
|
|
Suppressor
|
Various suppressor tRNAs, see Table 2 [[cgsc_site:supQ|CGSC]]
|-
|
tabC
|
86.3
|
T4 abortion
|
Mutants fail to support growth of T4 [[cgsc_site:125|CGSC]]
|-
|
tanA
|
41.6
|
Trehalose, anaerobic
|
Anaerobic growth on trehalose [[cgsc_site:37222|CGSC]]
|-
|
tanB
|
68.1
|
Trehalose, anaerobic
|
Anaerobic growth on trehalose [[cgsc_site:37910|CGSC]]
|-
|
tdi
|
4.3
|
Transduction inhibition
|
Affects transduction, transformation, and rates of mutation [[cgsc_site:121|CGSC]]
|-
|
thdA
|
10.5
|
Thiophene degradation
|
Degradation of furans and thiophenes; may be tlnA? [[cgsc_site:17824|CGSC]]
|-
|
thdC
|
94.2
|
Thiophene degradation
|
Degradation of furans and thiophenes [[cgsc_site:17821|CGSC]]
|-
|
thdD
|
99.8
|
Thiophene degradation
|
Degradation of furans and thiophenes [[cgsc_site:15908|CGSC]]
|-
|
tlnA
|
10.5
|
Thiolutin
|
tlnI; resistance or sensitivity to thiolutin; may be thdA? [[cgsc_site:102|CGSC]]
|-
|
tnm
|
92.0
|
Tn migration
|
Transposition of Tn9 and other transposons, development of phage Mu [[cgsc_site:100|CGSC]]
|-
|
tolD
|
22.9
|
Tolerance
|
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:96|CGSC]]
|-
|
tolE
|
22.9
|
Tolerance
|
Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin [[cgsc_site:95|CGSC]]
|-
|
tolI
|
0.1
|
Tolerance
|
Bacteriocin tolerant; sensitivity to colicins Ia and Ib [[cgsc_site:94|CGSC]]
|-
|
tolJ
|
0.1
|
Tolerance
|
Bacteriocin tolerant; sensitivity to L, A, S4, E, and K [[cgsc_site:93|CGSC]]
|-
|
tsmA
|
40.1
|
Thymine suppression modifier
|
Affects suppression efficiency for nonsense and frameshift mutations of Thy strains [[cgsc_site:36603|CGSC]]
|-
|
ups
|
27.1
|
Up-suppression?
|
Efficiency of nonsense suppressors; see prfA [[cgsc_site:23|CGSC]]
|-
|
uro
|
85.9
|
Uroporphyrinogen
|
hemC-Y operon [[cgsc_site:37849|CGSC]]
|-
|
uvh
|
90.2
|
UV hyperresistant to UVC
|
Resistance to UVC, peroxide and antibiotics; may affect SOS repair [[cgsc_site:51073|CGSC]]
|-
|
uvs
|
91.1
|
UV sensitivity
|
UV-sensitive mutants, locus linked to uvr [[cgsc_site:51076|CGSC]]


|-class='sortbottom'
|-class='sortbottom'

Revision as of 23:15, 26 September 2008

This page has a list of genes that are localized in the genetic map[1] but have not been assigned in the MG1655 or W3110 sequence annotation.

Gene Approx. Map Location Mnemonic Notes

abpS

63.5

Arg binding protein

Low-affinity transport system for arginine and ornithine; periplasmic binding protein CGSC

abs

94.1

Antibiotic sensitivity

Sensitivity and permeability to antibiotics and dyes CGSC

acpX

43.9

Acyl carrier protein

acpS; originally thought to be holo-ACP synthase; perhaps cryptic second gene or regulator CGSC

acrC

4.5

Acridine

Sensitivity to acriflavine; transmembrane protein CGSC

adhB

19.1

Alcohol dehydrogenase

Alcohol dehydrogenase CGSC

aga

70.7

Acetylgalactosamine

Cluster of putative N-acetylgalactosamine pathway genes, including the kba gene, and mannose permease homologs CGSC

aroI

84.2

Aromatic

Function unknown CGSC

att

17.3

Attachment

att92, att434; lambda attachment site CGSC

azaA

44.6

Azaserine

Mutants azaserine resistant CGSC

azaB

71.9

Azaserine

Mutants azaserine resistant CGSC

azl

58.1

Azaleucine

Mutants azaleucine resistant; regulates ilv and leu CGSC

bfm

85.9

BF23 multiplication

Controls phage BF23 multiplication CGSC

bglT

84.9

-Glucoside

bglE; regulatory gene for BglA CGSC

bioP

86.6

Biotin

bir, birB; biotin transport CGSC

brnR

8.5

Branched chain

Mutants valine resistant, glycylvaline sensitive CGSC

brnS

1.2

Branched chain

Mutants valine resistant, glycylvaline sensitive CGSC

brnT

65.2

Branched chain

Low-affinity transport of Ile CGSC

bymA

93.2

Bypass maltose

Growth on maltose in MalT cells CGSC

calA

95.0

Calcium

Calcium-proton antiport activity CGSC

calC

15.2

Calcium

Calcium transport; mutants defective in chemotaxis CGSC

calD

9.4

Calcium

Calcium transport; mutants defective in chemotaxis CGSC

cdsS

71.7

CDP diglyceride synthase

Stability of CDP diglyceride synthase CGSC

cpsA

45.4

Capsular polysaccharide synthesis

Colanic acid (CPS) biosynthesis CGSC

cpsC

45.8

Capsular polysaccharide synthesis

Colanic acid (CPS) biosynthesis CGSC

cpsD

45.8

Capsular polysaccharide synthesis

Colanic acid (CPS) biosynthesis CGSC

cpsE

45.8

Capsular polysaccharide synthesis

Colanic acid (CPS) biosynthesis CGSC

cpsF

90.2

Capsular polysaccharide synthesis

Colanic acid (CPS) biosynthesis CGSC

cpxB

41.3

Conjugative plasmid expression

Phage Q resistance, membrane protein CGSC

crg

28.8

Cold resistant growth

Allows cold-resistant growth CGSC

csiA

85.3

Carbon starvation induced

Stationary phase inducible protein CGSC

csiB

17.4

Carbon starvation induced

Stationary phase inducible protein CGSC

csiC

66.0

Carbon starvation induced

Stationary phase inducible protein CGSC

csiF

8.6

Carbon starvation induced

Stationary phase inducible protein CGSC

cup

97.0

Carbohydrate uptake

Mutants have defective carbohydrate uptake CGSC

cxm

6.3

Carbon-xylose metabolism

cxr; methyl glyoxal synthesis; D-xylose utilization CGSC

cysX

81.5

Cysteine

Reading frame in opposite orientation within cysE gene; polypeptide synthesized in maxicells CGSC

dadQ

98.9

D-Amino acid dehydrogenase

alnR; regulator of dad regulon CGSC

dctB

16.4

Dicarboxylic acid transport

Uptake of C-4 dicarboxylic acids; 3-fluoromalate resistance, D-tartrate resistant CGSC

del

64.3

Deletion

Affects frequency of IS1-mediated deletions; 1,000-fold reduction in deletion frequency CGSC

dgkR

93.7

Diglyceride kinase

Regulatory CGSC

dif

34.2

Deletion-induced filamentation

Recombination site in terminus, recA independent CGSC

dinY

41.9

Damage inducible

Repair gene CGSC

dnaI

40.3

DNA

DNA biosynthesis CGSC

dppG

14.0

Dipeptide permease

Uptake of dipeptides; dipeptide permease CGSC

dvl

7.4

Dye-visible light?

Sensitivity to SDS and toluidine blue plus light CGSC

ebgB

69.5

Evolved -galactosidase

Cryptic -galactoside utilization, possible paralog of lacY CGSC

envN

4.2

Envelope

Affects envelope; defects osmotically remedied CGSC

envP

90.4

Envelope

Affects envelope; defects osmotically remedied CGSC

envQ

60.7

Envelope

Affects envelope; defects osmotically remedied CGSC

envT

14.2

Envelope

Affects envelope; defects osmotically remedied CGSC

epp

E-pentapeptide

Minigene within 23S rRNA encoding functional pentapeptide; erythromycin resistance CGSC

esp

17.3

Efficiency site for phage

Site for efficient packaging of phage T1 CGSC

exbC

61.5

Export

Uptake of enterochelin; resistance or sensitivity to colicins CGSC

expA

22.2

Export

Expression of a group of export proteins CGSC

fatA

71.7

Fatty acid

Utilization of trans unsaturated fatty acids CGSC

fcsA

86.9

Filamentous, cold sensitive

Cold-sensitive cell division mutant CGSC

fexB

86.7

F exclusion

Affects ArcA phenotype CGSC

fhlB

95.1

Formate hydrogen-lyase

Formate hydrogen-lyase; activated by fhlA CGSC

fipB

86.0

F1 phage

Morphogenesis of phage F1 CGSC

fipC

75.0

F1 phage

Morphogenesis of phage F1 CGSC

flkB

95.4

FKBP-like

Periplasmic PPIase, of FK506-binding protein type (EC 5.2.1.8); contains pipecolic acid residue CGSC

gadR

79.6

Glutamate deCase

Regulatory gene for gat? CGSC

garA

15.8

Glucarate

D-Glucarate utilization CGSC

garB

3.6

Glucarate

D-Glucarate utilization CGSC

glmX

26.2

Glucosamine

Affects suppression of glmS mutations by nagB CGSC

gltE

81.4

Glutamate

Glutamyl-tRNA synthetase; possible regulatory subunit CGSC

gltH

21.8

Glutamate

Growth on glutamate CGSC

gltR

92.3

Glutamate

Growth on glutamate at 42C CGSC

gprA

0.3

Growth of phage, replication

Replication of certain lambdoid phage CGSC

gprB

0.2

Growth of phage, replication

Replication of certain lambdoid phage CGSC

gurC

18.0

Glucuronide

Utilization of glucuronides CGSC

het

84.6

Heterogeneous size

cop; possibly structural gene for DNA-binding protein; near ori CGSC

hslC

19.9

Heat shock locus

Protein expressed as heat shock regulon member CGSC

hslD

24.1

Heat shock locus

Protein expressed as heat shock regulon member CGSC

hslK

40.7

Heat shock locus

Protein expressed as heat shock regulon member CGSC

hslW

94.2

Heat shock locus

Heat-inducible; regulatory gene, near groE CGSC

ilvF

57.0

Isoleucine-valine (requirement)

Production of valine-resistant acetolactate synthase activity CGSC

ilvR

99.9

Isoleucine-valine 

CGSC

ilvU

6.4

Isoleucine-valine (requirement)

Regulation of ileS and modification of Ile tRNA2 and Val tRNA2 CGSC

inm

79.0

Insensitive NG mutagenesis

Susceptibility to mutagenesis by nitrosoguanidine CGSC

isfA

86.0

Inhibits SOS function

Regulatory gene; SOS-related CGSC

ksgB

37.7

Kasugamycin

High-level resistance to kasugamycin CGSC

ksgC

12.0

Kasugamycin

Resistance to kasugamycin; affects ribosomal protein S2 CGSC

ksgD

30.9

Kasugamycin

Resistance to kasugamycin CGSC

leuJ

13.7

Leucine (biosynthesis)

flr; regulation of leu and ilv operons CGSC

leuR

79.3

Leucine

Regulates level of leucyl-tRNA synthetase CGSC

leuY

9.5

Leucine

Regulates level of leucyl-tRNA synthetase CGSC

lev

9.0

Levallorphan

Resistance to levallorphan CGSC

linB

29.3

Lincomycin

High-level lincomycin resistance CGSC

lpcB

68.0

Lipopolysaccharide core

mrc, pon; T-phage resistance, novobiocin sensitivity CGSC

lrb

7.3

L-Ribose (utilization)

Affects NADPH-linked L-ribose reductase activity CGSC

lysX

63.3

Lysine

Lysine excretion CGSC

lytA

60.6

Lytic

Tolerance to -lactams; autolysis CGSC

mafA

0.9

Maintenance of F

Maintenance of F-like plasmids CGSC

mafB

1.9

Maintenance of F

Maintenance of F-like plasmids CGSC

mbrB

88.6

Mothball resistant

Resistance to camphor vapors; coupling of cell division and replication, growth rate and partitioning CGSC

meb

78.7

malE bypass

Suppressor of malE secB-defective transport of mal-binding protein CGSC

mglR

16.9

Methyl-galactoside

R-MG; regulatory gene CGSC

mms

69.2

Macromolecular synthesis

Complex operon, macromolecular synthesis CGSC

mng

40.0

Manganese

Manganese resistance CGSC

mraA

2.0

Murein cluster a

D-Alanine carboxypeptidase CGSC

mul

83.1

Mutability lambda

Mutability in UV-radiated lambda phage CGSC

murH

99.3

Murein

Terminal stage in peptidoglycan synthesis, incorporating disaccharide peptide units into wall CGSC

mutG

43.7

Mutator

Mutation causes high C-to-T mutation in second C of CCAGG; near but distinct from vsr; provisionally termed mutG CGSC

nalB

60.2

Nalidixic acid

Sensitivity to nalidixic acid (NAL) CGSC

neaB

75.0

Neamine

Neamine sensitivity CGSC

nfnA

80.8

Nitrofurantoin

Nitrofurantoin sensitivity CGSC

nfrD

54.2

N4 (phage) resistant

Phage N4 susceptibility CGSC

non

45.7

Nonmucoid

Affects capsule formation CGSC

oppE

98.9

Oligopeptide permease

Oligopeptide transport CGSC

opr

19.0

rpo reversed

Rate of degradation of aberrant RNAP-subunit proteins CGSC

ops

66.1

Overproduction of polysaccharide

Level of exopolysaccharide production CGSC

oriJ

30.5

Origin of replication

Locus in defective prophage rac CGSC

pac

31.0

Phenylacetate

Phenylacetate degradation CGSC

phxB

17.0

Phage X

Adsorption of X154 CGSC

poaR

65.9

Proline oxidase

Regulation of proline oxidase production CGSC

popD

0.2

Porphyrin

5-Aminolevulinate dehydratase (EC 4.2.1.24) CGSC

prlZ

71.4

Protein localization

Suppresses export defects in signal sequence mutations CGSC

proT

83.8

Proline

Proline transport carrier protein, putative CGSC

pus

20.6

Reverse of sup (amber)

Reverses accentuation effects of amber suppressor on relB mutations CGSC

qin

35.1

Q independent

kim; cryptic lambdoid phage CGSC

qmeC

75.3

Q membrane

Glycine resistance; penicillin sensitivity; membrane defect CGSC

qmeD

64.4

Q membrane

Glycine resistance; penicillin sensitivity; membrane defect CGSC

qmeE

37.9

Q membrane

Glycine resistance; penicillin sensitivity; membrane defect CGSC

ras

9.9

Radiation sensitive

Sensitive to X rays and UV CGSC

rdgA

16.1

RecA-dependent growth

Dependence of growth upon recA gene product CGSC

relX

62.8

Relaxed

Control of ppGpp synthesis CGSC

rer

89.9

Resistance to radiation

Resistance to UV and gamma radiation CGSC

ridA

73.1

Rifampin dependence

Rifampin resistance and dependence CGSC

ridB

85.5

Rifampin dependence

Transcription and translation; rifampin (rifamycin) sensitivity CGSC

rimB

38.9

Ribosomal modification

50S ribosomal subunit maturation CGSC

rimC

26.2

Ribosomal modification

50S ribosomal subunit maturation CGSC

rimD

87.7

Ribosomal modification

50S ribosomal subunit maturation CGSC

rimE

74.1

Ribosomal modification

Ribosomal protein modification CGSC

rimH

13.6

Ribosomal modification

stsB; ribosomal modification CGSC

rit

89.2

Ribosomal thermolability

Affects thermolability of 50S ribosomal subunit CGSC

rorB

85.1

Roentgen resistance

Sensitivity to ionizing radiation, mitomycin C CGSC

rrnA

96.9

Ribosomal RNA (operon)

See Fig. 1 CGSC

rrnB

89.8

Ribosomal RNA (operon)

cqsE, rrnB1; see Fig. 1 CGSC

rrnC

84.9

Ribosomal RNA (operon)

cqsB; see Fig. 1 CGSC

rrnD

73.7

Ribosomal RNA (operon)

cqsD; see Fig. 1 CGSC

rrnE

90.7

Ribosomal RNA (operon)

rrnD1; see Fig. 1 CGSC

rrnG

58.7

Ribosomal RNA (operon)

See Fig. 1 CGSC

rrnH

4.8

Ribosomal RNA (operon)

See Fig. 1 CGSC

sds

30.4

Suppresses disulfide bond

Motility defects CGSC

semA

40.5

Sensitivity to microcin

Sensitivity to microcin E492 CGSC

serR

2.3

Serine

Regulates level of seryl-tRNA synthetase CGSC

sfiC

25.8

Septum formation inhibition

Element of e14, inhibitor of cell division CGSC

sipC

82.6

Suppressor of increased permeability

Mutations reverse the susceptibility to vancomycin and other hydrophobic antibiotics caused by TraT plasmid gene CGSC

sipD

82.7

Suppressor of increased permeability

Same phenotype as that produced by sipC CGSC

sir

61.2

SOS-independent repair

SOS-independent repair of mitomycin C-induced DNA damage CGSC

sloB

75.0

Slow growth

Tolerance for amidinopenicillin and nalidixic acid; slow growth rate CGSC

slrR

60.9

Sorbitol

gutR; regulatory gene for srl CGSC

srnA

9.4

Stable RNA

Degradation of stable RNA CGSC

ssaE

52.5

Suppression secA

Suppresses secA mutations CGSC

ssaG

41.8

Suppression secA

Suppresses secA mutations CGSC

ssaH

94.1

Suppression secA

Suppresses secA mutations CGSC

ssyD

3.0

Suppression of secY

Suppressor of secY mutation CGSC

stfZ

2.3

fts in reverse

Antisense RNA blocks ftsZ mRNA translation, inhibits cell division CGSC

stkA

77.5

Suppressor of transposase killing

Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC

stkB

86.1

Suppressor of transposase killing

Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC

stkC

98.5

Suppressor of transposase killing

Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC

stkD

28.6

Suppressor of transposase killing

Suppresses cell aberrations and death caused by Tn5 transposase overexpression CGSC

strC

7.0

Streptomycin

strB; low-level streptomycin resistance; modifies ribosome structure CGSC

strM

78.3

Streptomycin

asuF?; control of ribosomal ambiguity CGSC

stsA

84.7

Altered RNase activity CGSC

suhA

78.4

Suppressor heat-shock proteins

Induction of heat shock genes CGSC

sup

Suppressor

Various suppressor tRNAs, see Table 2 CGSC

tabC

86.3

T4 abortion

Mutants fail to support growth of T4 CGSC

tanA

41.6

Trehalose, anaerobic

Anaerobic growth on trehalose CGSC

tanB

68.1

Trehalose, anaerobic

Anaerobic growth on trehalose CGSC

tdi

4.3

Transduction inhibition

Affects transduction, transformation, and rates of mutation CGSC

thdA

10.5

Thiophene degradation

Degradation of furans and thiophenes; may be tlnA? CGSC

thdC

94.2

Thiophene degradation

Degradation of furans and thiophenes CGSC

thdD

99.8

Thiophene degradation

Degradation of furans and thiophenes CGSC

tlnA

10.5

Thiolutin

tlnI; resistance or sensitivity to thiolutin; may be thdA? CGSC

tnm

92.0

Tn migration

Transposition of Tn9 and other transposons, development of phage Mu CGSC

tolD

22.9

Tolerance

Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin CGSC

tolE

22.9

Tolerance

Bacteriocin tolerant; tolerance to colicins E2, E3, and ampicillin CGSC

tolI

0.1

Tolerance

Bacteriocin tolerant; sensitivity to colicins Ia and Ib CGSC

tolJ

0.1

Tolerance

Bacteriocin tolerant; sensitivity to L, A, S4, E, and K CGSC

tsmA

40.1

Thymine suppression modifier

Affects suppression efficiency for nonsense and frameshift mutations of Thy strains CGSC

ups

27.1

Up-suppression?

Efficiency of nonsense suppressors; see prfA CGSC

uro

85.9

Uroporphyrinogen

hemC-Y operon CGSC

uvh

90.2

UV hyperresistant to UVC

Resistance to UVC, peroxide and antibiotics; may affect SOS repair CGSC

uvs

91.1

UV sensitivity

UV-sensitive mutants, locus linked to uvr CGSC

edit table


References

See Help:References for how to manage references in EcoliWiki.

  1. ↑ Berlyn, MK (1998) Linkage map of Escherichia coli K-12, edition 10: the traditional map. Microbiol. Mol. Biol. Rev. 62 814-984 PubMed
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