folK:Quickview: Difference between revisions

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[http://ecoliwiki.net/tools/display_dna.php?gene=folK&loc=MG1655:157732..157253,W3110:157732..157253,DH10B:131836..131357,REL606:160583..160104,BW2952:157252..157731 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=157252&end=157731&gene=folK&aa=mtvayiaigsnlaspleqvnaalkalgdipeshiltvssfyrtpplgpqdqpdylnaavaletslapeellnhtqrielqqgrvrkaerwgprtldldimlfgnevinterltvphydmknrgfmlwplfeiapelvfpdgemlrqilhtrafdklnkw Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=folK+AND+escherichia+coli Pubmed(folK)]    [http://trimer.tamu.edu/cgi-bin/textpresso/search?q=folK Textpresso(folK)]
[http://porteco.org/AjaxSearch.jsp?searchString=folK&s=search PortEco search(folK)]    [http://ecoliwiki.net/tools/display_dna.php?gene=folK&loc=MG1655:157732..157253,W3110:157732..157253,DH10B:131836..131357,REL606:160583..160104,BW2952:157252..157731 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=157252&end=157731&gene=folK&aa=mtvayiaigsnlaspleqvnaalkalgdipeshiltvssfyrtpplgpqdqpdylnaavaletslapeellnhtqrielqqgrvrkaerwgprtldldimlfgnevinterltvphydmknrgfmlwplfeiapelvfpdgemlrqilhtrafdklnkw Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=folK+AND+escherichia+coli Pubmed(folK)]    [http://trimer.tamu.edu/cgi-bin/textpresso/search?q=folK Textpresso(folK)]


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Revision as of 08:11, 27 May 2011

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

folK

Gene Synonym(s)

ECK0141, b0142, JW0138[1]

Product Desc.

H2PTERIDINEPYROPHOSPHOKIN[2][3]

6-Hydroxymethyl-7,8-dihydropterin pyrophosphokinase; monomeric[4]

Product Synonyms(s)

2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase[1], HPPK[2][1], B0142[2][1], FolK[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): pcnB-folK[2]

Regulation/Activity
Quick Links

PortEco search(folK)    DNA display    Protein display    Pubmed(folK)    Textpresso(folK)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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HPPK active center is formed once both substrates, ATP and HP, are bound and this assembly results in confirmational changes primarily in catalytic loops 1-3; catalytic loop 3 moves in the opposite direction upon binding of the nucleotide. Catalytic loop 3 is involved in ternary complex stabilization and is necessary for catalysis.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.