yjjG:Quickview: Difference between revisions
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[http://ecoliwiki.net/tools/display_dna.php?gene=yjjG&loc=MG1655:4606669..4607346,W3110:4613326..4614003,DH10B:4653131..4653808,REL606:4597880..4598557 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start= | [http://ecoliwiki.net/tools/display_dna.php?gene=yjjG&loc=MG1655:4606669..4607346,W3110:4613326..4614003,DH10B:4653131..4653808,REL606:4597880..4598557,BW2952:4545153..4545830 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4545153&end=4545830&gene=yjjG&aa=mkwdwiffdadetlftfdsftglqrmfldysvtftaedfqdyqavnkplwvdyqngaitslqlqhgrfeswaerlnvepgklneafinamaeictplpgavsllnairgnakigiitngfsalqqvrlertglrdyfdllviseevgvakpnkkifdyaleqagnpdrsrvlmvgdtaesdilgginaglatcwlnahhreqpegiaptwtvsslheleqllckh Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=yjjG+AND+escherichia+coli Pubmed(yjjG)] [http://trimer.tamu.edu/cgi-bin/textpresso/search?q=yjjG Textpresso(yjjG)] | ||
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Revision as of 15:57, 12 April 2011
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
yjjG |
|---|---|
| Gene Synonym(s) |
ECK4365, b4374, JW4336[1] |
| Product Desc. |
Noncanonical pyrimidine nucleotide house-cleaning phosphatase; dUMP phosphatase activity[4] |
| Product Synonyms(s) | |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
Efficient in vitro substrates include: dUMP, UMP, and dTMP; phosphoramidase: in vitro activities demonstrated by Kuznetsova et al. (2005, 2006). yjjG mutants are sensitive to 5-fluoropyrimidine derivatives, such as 5-fluoro-2'-deoxyuridine (Titz, 2007). YjjG has a strict metal requirement for catalytic activity. Poorly utilized substrates include UDP, TDP and a variety of nucleotide monophosphates. A yjjG mutation blocks the utilization of thymine to feed a thyA auxotroph since it must first be converted to thymidine and dUMP dephosphorylated by YjjG is needed for that conversion (Weiss, 2006). YjjG is also called nucleoside 5'-monophosphate phosphohydrolase. HAD superfamily.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.