msbA:Quickview: Difference between revisions

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Revision as of 18:16, 17 June 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

msbA

Gene Synonym(s)

ECK0905, b0914, JW0897[1]

Product Desc.

ATP-binding transport protein[2][3]

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4]

Product Synonyms(s)

fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ycaI[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(msbA)    Textpresso(msbA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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MsbA PDB structures 1JSQ, 1PF4 and 1Z2R, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Chang, 2006). A yhjD point mutation (R134C) allows the deletion of the otherwise essential msbA gene (Mamat, 2007). MsbA point mutations confering S18P or S50P suppress the lethal phenotype of a KDO null gutQ kdsD double mutant (Mamat, 2007).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.