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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Cellular Component'''
<GO_nr />
* GO:0005737 cytoplasm ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype

Revision as of 19:44, 2 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

dksA

Gene Synonym(s)

ECK0144, b0145, JW0141, msmA[1]

Product Desc.

RNAP-binding transcriptional regulator of rRNA transcription[2][3]

RNAP-binding protein modulating ppGpp and iNTP regulation; reduces open complex half-life on rRNA promoters[4]

Product Synonyms(s)

RNAP-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein[1], B0145[2][1], MsmA[2][1], DksA[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s):

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(dksA)    Textpresso(dksA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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High copy dksA suppresses mukB and TS growth and filamentation of a dnaK mutant. dksA is also a multicopy suppressor of dnaJ, grpE and prc. dksA transcription is alkali-inducible. Mutations affect chromosomal supercoiling. Binds TrxA (Kumar, 2004). HT_Cmplx24_Cyt: DksA+GreA. dksA and ybiI are paralogs.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.