ubiE:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''ubiE''  
''ubiE''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3827, b3833, JW5581, yigO''<ref name='LIB:Riley_2006'/>
''ECK3827, b3833, JW5581, yigO''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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2-OCTAPRENYL-METHOXY-BENZOQ-METH<ref name='LIB:EcoCyc10.6'/>; bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase<ref name='LIB:EcoCyc11.1'/>
2-OCTAPRENYL-METHOXY-BENZOQ-METH<ref name='LIB:EcoCyc10.6'/>; bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase<ref name='LIB:EcoCyc11.1'/>
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Ubiquinone/menaquinone biosynthesis methyltransferase; SAM-dependent; (1) Ubiqinone synthesis, 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; (2) Menaquinone synthesis, 2-demethylmenaquinone (DMK) methyltransferase<ref name='LIB:EcoGene'/>
Ubiquinone/menaquinone biosynthesis methyltransferase; SAM-dependent; (1) Ubiqinone synthesis, 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; (2) Menaquinone synthesis, 2-demethylmenaquinone (DMK) methyltransferase<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase<ref name='LIB:Riley_2006'/>, B3833<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YigO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UbiE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase<ref name='LIB:Riley_2006'/>, B3833<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YigO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UbiE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0006744 ubiquinone biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0009234 menaquinone biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0008757 S-adenosylmethionine-dependent methyltransferase activity ([http://www.geneontology.org/GO.evidence.shtml HINF])
* GO:0043333 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0030580 quinone cofactor methyltransferase activity ([http://www.geneontology.org/GO.evidence.shtml IMP])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:ubiE-yigP-ubiB|ubiE-yigP-ubiB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:ubiE-yigP-ubiB|ubiE-yigP-ubiB]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=ubiE&loc=MG1655:4016878..4017633,W3110:3617826..3617071,REL606:3997326..3998081,DH10B:4115798..4116553 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4115798&end=4116553&gene=ubiE&aa=mvdksqetthfgfqtvakeqkadmvahvfhsvaskydvmndlmsfgihrlwkrftidcsgvrrgqtvldlaggtgdltakfsrlvgetgkvvladinesmlkmgreklrnigvignveyvqanaealpfpdntfdcitisfglrnvtdkdkalrsmyrvlkpggrllvlefskpiieplskaydaysfhvlprigslvandadsyrylaesirmhpdqdtlkammqdagfesvdyynltagvvalhrgykf Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=ubiE+AND+escherichia+coli Pubmed(ubiE)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=ubiE Textpresso(ubiE)]


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Revision as of 23:26, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

ubiE

Gene Synonym(s)

ECK3827, b3833, JW5581, yigO[1]

Product Desc.

2-OCTAPRENYL-METHOXY-BENZOQ-METH[2]; bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase[3]

Ubiquinone/menaquinone biosynthesis methyltransferase; SAM-dependent; (1) Ubiqinone synthesis, 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase; (2) Menaquinone synthesis, 2-demethylmenaquinone (DMK) methyltransferase[4]

Product Synonyms(s)

bifunctional 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase and S-adenosylmethionine:2-DMK methyltransferase[1], B3833[2][1], YigO[2][1], UbiE[2][1]

Function from GO

Biological Process

Molecular Function

  • GO:0008757 S-adenosylmethionine-dependent methyltransferase activity (HINF)
  • GO:0043333 2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity (IMP)
  • GO:0030580 quinone cofactor methyltransferase activity (IMP)
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): ubiE-yigP-ubiB[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(ubiE)    Textpresso(ubiE)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

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UbiE is the closest E. coli homolog to B. stearothermophilus MenG (MenH, SP O86169). ubiE mutants accumulate DMK, not MK. rraA (menG) does not encode a methyltransferase. Binds TrxA (Kumar, 2004).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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