secB:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''secB''  
''secB''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3599, b3609, JW3584''<ref name='LIB:Riley_2006'/>
''ECK3599, b3609, JW3584''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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SecB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
SecB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Protein export chaperone; SecB helps SecA deliver proteins to the SecYE core translocon; general protein chaperone<ref name='LIB:EcoGene'/>
Protein export chaperone; SecB helps SecA deliver proteins to the SecYE core translocon; general protein chaperone<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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protein export chaperone<ref name='LIB:Riley_2006'/>, B3609<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SecB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
protein export chaperone<ref name='LIB:Riley_2006'/>, B3609<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SecB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0006605 protein targeting ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0015031 protein transport ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0043952 protein transport by the Sec complex ([http://www.geneontology.org/GO.evidence.shtml IMP])
'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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non lethal. SecB null strains are deficient in post translational targeting of some secretion and outer membrane proteins.<ref name=PMID:3891730/>
non lethal. SecB null strains are deficient in post translational targeting of some secretion and outer membrane proteins.<ref name=PMID:3891730/>
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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:gpsA|gpsA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:gpsA|gpsA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=secB&loc=MG1655:3782151..3781684,W3110:3856287..3856754,REL606:3724894..3724427,DH10B:3879728..3879261 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3879728&end=3879261&gene=secB&aa=mseqnntemtfqiqriytkdisfeapnaphvfqkdwqpevkldldtassqladdvyevvlrvtvtaslgeetaflcevqqggifsiagiegtqmahclgaycpnilfpyarecitsmvsrgtfpqlnlapvnfdalfmnylqqqagegteehqda Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=secB+AND+escherichia+coli Pubmed(secB)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=secB Textpresso(secB)]


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Revision as of 23:32, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

secB

Gene Synonym(s)

ECK3599, b3609, JW3584[1]

Product Desc.

SecB[2][3];

Component of Sec Protein Secretion Complex[2][3]

Protein export chaperone; SecB helps SecA deliver proteins to the SecYE core translocon; general protein chaperone[4]

Product Synonyms(s)

protein export chaperone[1], B3609[2][1], SecB[2][1]

Function from GO

Biological Process

Molecular Function

Knock-Out Phenotype

non lethal. SecB null strains are deficient in post translational targeting of some secretion and outer membrane proteins.[5]

Regulation/Expression

transcription unit(s): gpsA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(secB)    Textpresso(secB)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


Penultimate Ser residue missing from purified protein could be a proteolytic artifact.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Kumamoto, CA & Beckwith, J (1985) Evidence for specificity at an early step in protein export in Escherichia coli. J. Bacteriol. 163 267-74 PubMed
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