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{{Tab On|Quickview|waaA}}{{Tab|Gene|waaA}}{{Tab|Gene Product(s)|waaA}}{{Tab|Expression|waaA}}{{Tab|Evolution|waaA}}{{Tab|On One Page|waaA}}{{TabsBottom}}
{{Tab On|Quickview|waaA}}{{Tab|Gene|waaA}}{{Tab|Gene Product(s)|waaA}}{{Tab|Expression|waaA}}{{Tab|Evolution|waaA}}{{Tab|On One Page|waaA}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[waaA:Gene|''waaA]]'' (synonyms: ''kdtA, ECK3623, b3633, JW3608'')<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/>
''waaA''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[waaA:Gene_Product(s)|KdtA product]]<ref name='LIB:Riley_2006'/>: 3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase) product, B3633 product, WaaA product
''kdtA, ECK3623, b3633, JW3608''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc11.1'/>, JW3608''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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KDOTRANS-MONOMER<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
3-deoxy-D-manno-octulosonate(Kdo)-lipid A transferase<ref name='LIB:EcoGene'/>
 
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)<ref name='LIB:Riley_2006'/>, B3633<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, WaaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, KdtA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3623, JW3608, kdtA, b3633''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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lethal (see PMID:7499229)
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:kdtA|kdtA]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:kdtA-coaD|kdtA-coaD]]<ref name='LIB:EcoCyc10.6'/>, kdtAB, waaA-coaD  
transcription unit(s): [[:Category:Txn_unit:kdtA|kdtA]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:kdtA-coaD|kdtA-coaD]]<ref name='LIB:EcoCyc10.6'/>, kdtAB, waaA-coaD  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=waaA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10520]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000513&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=waaA&loc=MG1655%3A3806563..3807840,W3110%3A3831875..3830598,REL606%3A3746895..3748172,BW2952%3A3694889..3696166]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3694889&end=3696166&gene=waaA&aa=mlellytallyliqpliwirlwvrgrkapayrkrwgerygfyrhplkpggimlhsvsvgetlaaiplvralrhrypdlpitvttmtptgservqsafgkdvqhvylpydlpdalnrflnkvdpklvlimetelwpnliaalhkrkiplvianarlsarsaagyaklgkfvrrllrritliaaqneedgarfvalgaknnqvtvtgslkfdisvtpqlaakavtlrrqwaphrpvwiatsthegeesvviaahqallqqfpnlllilvprhperfpdainlvrqaglsyitrssgevpststqvvvgdtmgelmllygiadlafvggslvergghnpleaaahaipvlmgphtfnfkdicarleqasglitvtdattlakevsslltdadyrsfygrhavevlyqnqgalqrllqllepylppkth]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=waaA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=waaA]]&nbsp;&nbsp;
 
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==Notes==
===Notes===
{{BacktoTop}}
 
WaaA adds 2 Kdo residues to lipid IVA.  waaA is an essential gene.  Mutagenesis eliminated ATG a codon 52 as a start codon (Belunis and Raetz, 1992).<ref name='LIB:EcoGene'/>
 




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==References==
==References==
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Latest revision as of 21:45, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

waaA

Gene Synonym(s)

kdtA, ECK3623, b3633, JW3608[1][2], JW3608

Product Desc.

3-deoxy-D-manno-octulosonate(Kdo)-lipid A transferase[3]

Product Synonyms(s)

3-deoxy-D-manno-octulosonic-acid transferase (KDO transferase)[1], B3633[4][1], WaaA[4][1], KdtA[4][1] , ECK3623, JW3608, kdtA, b3633

Function from GO

<GO_nr />

Knock-Out Phenotype

lethal (see PMID:7499229[5])

Regulation/Expression

transcription unit(s): kdtA[4], kdtA-coaD[4], kdtAB, waaA-coaD

Regulation/Activity
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Notes

[back to top]


WaaA adds 2 Kdo residues to lipid IVA. waaA is an essential gene. Mutagenesis eliminated ATG a codon 52 as a start codon (Belunis and Raetz, 1992).[3]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ Belunis, CJ et al. (1995) Inhibition of lipopolysaccharide biosynthesis and cell growth following inactivation of the kdtA gene in Escherichia coli. J. Biol. Chem. 270 27646-52 PubMed
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