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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''plsX''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1076, b1090, JW5156''<ref name='LIB:Riley_2006'/>, JW5156''
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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fatty acid/phospholipid synthesis protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
Probable phosphate:acyl-ACP acyltransferase; confers glycerol phosphate auxotrophy, when combined with a plsB Km missense mutant<ref name='LIB:EcoGene'/>
|-
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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''fatty acid/phospholipid synthesis protein<ref name='LIB:Riley_2006'/>, B1090<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PlsX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1076, JW5156, b1090''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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|-
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:plsX-fabHDG|plsX-fabHDG]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:rpmF-plsX-fabHDG|rpmF-plsX-fabHDG]]<ref name='LIB:EcoCyc10.6'/>
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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|-
!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=plsX&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11437]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001401&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=plsX&loc=MG1655%3A1146844..1147914,W3110%3A1149198..1150268,DH10B%3A1202289..1203359,REL606%3A1162190..1163260,BW2952%3A1050769..1051839]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1050769&end=1051839&gene=plsX&aa=mggdfgpsvtvpaalqalnsnsqltlllvgnsdaitpllakadfeqrsrlqiipaqsviasdarpsqairasrgssmrvalelvkegraqacvsagntgalmglaklllkplegierpalvtvlphqqkgktvvldlganvdcdstmlvqfaimgsvlaeevveipnprvallnigeeevkgldsirdasavlktipsinyigyleanelltgktdvlvcdgftgnvtlktmegvvrmflsllksqgegkkrswwllllkrwlqksltrrfshlnpdqyngacllglrgtvikshgaanqrafavaieqavqavqrqvpqriaarlesvypagfelldggksgtlr]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=plsX+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=plsX]]&nbsp;&nbsp;


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PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProt: Q97TA6) (Lu, 2006).  ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.<ref name='LIB:EcoGene'/>
PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProtKB:Q97TA6) (Lu, 2006).  ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.<ref name='LIB:EcoGene'/>






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==References==
==References==
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Latest revision as of 03:08, 30 June 2019

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

plsX

Gene Synonym(s)

ECK1076, b1090, JW5156[1], JW5156

Product Desc.

fatty acid/phospholipid synthesis protein[2][3]

Probable phosphate:acyl-ACP acyltransferase; confers glycerol phosphate auxotrophy, when combined with a plsB Km missense mutant[4]

Product Synonyms(s)

fatty acid/phospholipid synthesis protein[1], B1090[2][1], PlsX[2][1] , ECK1076, JW5156, b1090

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): plsX-fabHDG[2], rpmF-plsX-fabHDG[2]

Regulation/Activity
Quick Links



        

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Notes

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PlsX is homologous to the S. pneumoniae phosphate:acyl-ACP acyltransferase PlsX (UniProtKB:Q97TA6) (Lu, 2006). ygiH(plsY) and plsX are synthetic lethals (Yoshimura, 2007). S. pneumoniae PlsX and PlsY work together as a two-step glycerol-3-phosphate acylation, the first step in phosphatidic acid synthesis, an intermediate in phospholipid synthesis (Lu, 2006). PlsXY homologs are present in E. coli, but PlsXY apparently cannot substitute for the single step reaction catalyzed by PlsB, which is essental in E. coli.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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