basR:Quickview: Difference between revisions

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{|   id="R49aee0f505e33" class=" tableEdit New_Quickview_Table"


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!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[basR:Gene|''basR]]'' (synonyms: ''ECK4106, b4113, JW4074, pmrA'')<ref name='LIB:Riley_2006'/>
''basR''
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!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[basR:Gene_Product(s)|BasR product, BasR product]]<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>: B4113 product, PmrA product, transcriptional regulatory protein BasR product, unphosphorylated transcriptional regulatory protein BasR product, unmodified transcriptional regulatory protein BasR product
''ECK4106, b4113, JW4074, pmrA''<ref name='LIB:Riley_2006'/>, pmrA''
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!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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BasR transcriptional regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
DNA-binding response regulator in two-component regulatory system with BasS<ref name='LIB:Riley_2006'/>


Response regulator for Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
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''PmrA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, B4113<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ECK4106, JW4074, pmrA, b4113''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:basRS|basRS]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:basRS|basRS]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=basR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11615]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120001563&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=basR&loc=MG1655%3A4331973..4331305,W3110%3A4338628..4337960,DH10B%3A4432335..4431667,REL606%3A4312664..4311996,BW2952%3A4270040..4270708]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4270040&end=4270708&gene=basR&aa=mkiliveddtlllqglilaaqtegyacdsvttarmaeqsleaghyslvvldlglpdedglhflarirqkkytlpvliltardtltdkiagldvgaddylvkpfaleelharirallrrhnnqgeselivgnltlnmgrrqvwmggeeliltpkeyallsrlmlkagspvhreilyndiynwdnepstntlevhihnlrdkvgkarirtvrgfgymlvaneen]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=basR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=basR]]&nbsp;&nbsp;


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Latest revision as of 21:52, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

basR

Gene Synonym(s)

ECK4106, b4113, JW4074, pmrA[1], pmrA

Product Desc.

DNA-binding response regulator in two-component regulatory system with BasS[1]

Response regulator for Lipid A modification genes; two-component system involved in polymyxin resistance that senses high extracellular Fe(2+)[2]

Product Synonyms(s)

PmrA[3][1], B4113[3][1], ECK4106, JW4074, pmrA, b4113

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): basRS[3]

Regulation/Activity
Quick Links



        

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See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


BasS is the cognate sensor protein of the BasSR two-component system. Constitutive allele basR53 (pmrA53) confers polymyxin B resistance and deoxycholate hypersensitivity. EvgAS regulon. BasSR confers resistance to Fe(III)-mediated killing.The BasSR regulon has been primarily characterized in Salmonella; unlike E. coli, Salmonella also activates PmrAB(BasSR) in low Mg(2+), mediated by PhoPQ and the PmrD protein.[2]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
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