mrcB:Quickview: Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older edit
imported>Wikientrybot
Move help links into the <above> tag inside templates.
touch
 
(12 intermediate revisions by 2 users not shown)
Line 17: Line 17:
|}
|}
</noinclude>
</noinclude>
<!--box uid=421aa90e079fa326b6494f812ad13e79.2059.I46a99ba517a99-->
<protect><!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527-->
<!--
<!--
******************************************************************************************
******************************************************************************************
Line 24: Line 24:
*  
*  
****************************************************************************************** -->
****************************************************************************************** -->
{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  
{|   id="G49aeed2dec527" class=" tableEdit New_Quickview_Table"


|-
|-
!align=left {{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
||
||
[[mrcB:Gene|''mrcB]]'' (synonyms: ''ECK0148, b0149, JW0145, pbpF, ponB'')<ref name='LIB:Riley_2006'/>
''mrcB''
|-
|-
!align=left {{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
||
||
[[mrcB:Gene_Product(s)|MrcB product]]<ref name='LIB:Riley_2006'/>: fused glycosyl transferase product, transpeptidase product, B0149 product, PonB product, PbpF product, PBP1B product
''ECK0148, b0149, JW0145, pbpF, ponB''<ref name='LIB:Riley_2006'/>, ponB''
|-
|-
!align=left {{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
||
||
MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>  
MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;


Component of [[:Category:Complex:penicillin-binding protein 1B|penicillin-binding protein 1B]]<ref name='LIB:EcoCyc11.1'/>
Component of [[:Category:Complex:penicillin-binding protein 1B|penicillin-binding protein 1B]]<ref name='LIB:EcoCyc11.1'/>


Murein polymerase, PBP1B; bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein 1B; dimeric<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Product Synonyms(s)
||
''fused glycosyl transferase<ref name='LIB:Riley_2006'/>, transpeptidase<ref name='LIB:Riley_2006'/>, B0149<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PonB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PbpF<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MrcB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PBP1B<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0148, JW0145, pbpF, ponB, b0149''
|-
!align=left {{table_heading_style}} |Function from GO
||
<GO_nr />
|-
!align=left {{table_heading_style}} |Knock-Out Phenotype
||
||


|-
|-
!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
||
||
transcription unit(s): [[:Category:Txn_unit:mrcB|mrcB]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mrcB|mrcB]]<ref name='LIB:EcoCyc10.6'/>  
Line 53: Line 62:
||
||


|-
!align=left {{table_heading_style}} |Quick Links
||
[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mrcB&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10605]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000598&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mrcB&loc=MG1655%3A164730..167264,W3110%3A164730..167264,DH10B%3A138834..141368,REL606%3A167581..170106,BW2952%3A164729..167263]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=164729&end=167263&gene=mrcB&aa=magndrepigrkgkptrpvkqkvsrrryeddddyddyddyedeepmprkgkgkgkgrkprgkrgwlwlllklaivfavliaiygvyldqkirsridgkvwqlpaavygrmvnlepdmtisknemvklleatqyrqvskmtrpgeftvqansiemirrpfdfpdskegqvrarltfdgdhlativnmennrqfgffrldprlitmisspngeqrlfvprsgfpdllvdtllatedrhfyehdgislysigravlanltagrtvqgastltqqlvknlflssersywrkaneaymalimdaryskdrilelymnevylgqsgdneirgfplaslyyfgrpveelsldqqallvgmvkgasiynpwrnpklalerrnlvlrllqqqqiidqelydmlsarplgvqprggvispqpafmqlvrqelqaklgdkvkdlsgvkifttfdsvaqdaaekaavegipalkkqrklsdletaivvvdrfsgevramvggsepqfagynramqarrsigslakpatyltalsqpkiyrlntwiadapialrqpngqvwspqnddrrysesgrvmlvdaltrsmnvptvnlgmalglpavtetwiklgvpkdqlhpvpamllgalnltpievaqafqtiasggnraplsalrsviaedgkvlyqsfpqaeravpaqaayltlwtmqqvvqrgtgrqlgakypnlhlagktgttnnnvdtwfagidgstvtitwvgrdnnqptklygasgamsiyqrylanqtptplnlvppediadmgvdydgnfvcsggmrilpvwtsdpqslcqqsemqqqpsgnpfdqssqpqqqpqqqpaqqeqkdsdgvagwikdmfgsn]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mrcB+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mrcB]]&nbsp;&nbsp;


|-class='sortbottom'
|- class="tableEdit_footer"
|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.2059.I46a99ba517a99&page=2059&pagename={{FULLPAGENAMEE}}&type=1&template=Quickview_table edit table] ||
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527&page=2059&pagename={{FULLPAGENAMEE}}&type=1&template=New_Quickview_Table edit table]</span> ||
|}
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.2059.I46a99ba517a99-->
<!--box uid=bc145ea147f7e36caf09c1bfeed4ee9d.2059.G49aeed2dec527--></protect>
{{Quickview_table_help}}
{{Quickview_table_help}}
<protect><!--Quickview_notes--></protect>
<protect><!--Quickview_notes--></protect>
===Notes===
===Notes===
{{BacktoTop}}
{{BacktoTop}}
MrcB is part of a complex with MltA and MipA. The N-terminal transglycosylase activity polymerizes the glycan backbone and is penicillin-insensitive. The C-terminal transpeptidase activity crosslinks the muramic peptides and is penicillin-sensitive. Full length MrcB is the alpha isoform. A second in vivo ATG start at codon 46 produces the 799 aa gamma isoform. Murein polymerase is an essential function satisfied by either MrcA or MrcB. Mutants have elevated OM vesiculation (McBroom, 2006). MrcB is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor.<ref name='LIB:EcoGene'/>




Latest revision as of 21:47, 27 May 2013

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

mrcB

Gene Synonym(s)

ECK0148, b0149, JW0145, pbpF, ponB[1], ponB

Product Desc.

MrcB[2][3];

Component of penicillin-binding protein 1B[3]

Murein polymerase, PBP1B; bifunctional murein transglycosylase and transpeptidase; penicillin-binding protein 1B; dimeric[4]

Product Synonyms(s)

fused glycosyl transferase[1], transpeptidase[1], B0149[2][1], PonB[2][1], PbpF[2][1], MrcB[2][1], PBP1B[2][1] , ECK0148, JW0145, pbpF, ponB, b0149

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mrcB[2]

Regulation/Activity
Quick Links



        

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


MrcB is part of a complex with MltA and MipA. The N-terminal transglycosylase activity polymerizes the glycan backbone and is penicillin-insensitive. The C-terminal transpeptidase activity crosslinks the muramic peptides and is penicillin-sensitive. Full length MrcB is the alpha isoform. A second in vivo ATG start at codon 46 produces the 799 aa gamma isoform. Murein polymerase is an essential function satisfied by either MrcA or MrcB. Mutants have elevated OM vesiculation (McBroom, 2006). MrcB is a membrane-bound periplasmic enzyme that has an uncleaved signal anchor.[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=mrcB:Quickview&oldid=1396418"