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{{Tab On|Quickview|deoR}}{{Tab|Gene|deoR}}{{Tab|Gene Product(s)|deoR}}{{Tab|Expression|deoR}}{{Tab|Evolution|deoR}}{{Tab|On One Page|deoR}}{{TabsBottom}}
{{Tab On|Quickview|deoR}}{{Tab|Gene|deoR}}{{Tab|Gene Product(s)|deoR}}{{Tab|Expression|deoR}}{{Tab|Evolution|deoR}}{{Tab|On One Page|deoR}}{{TabsBottom}}
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!{{table_heading_style}} |Gene Name
!align=left {{table_heading_style}} |Standard Name
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[[deoR:Gene|''deoR]]'' (synonyms: ''ECK0830, b0840, JW0824, nucR'')<ref name='LIB:Riley_2006'/>
''deoR''
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!{{table_heading_style}} |Product(s)  
!align=left {{table_heading_style}} |Gene Synonym(s)
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[[deoR:Gene_Product(s)|DeoR product]]<ref name='LIB:Riley_2006'/>: DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B0840<ref name='LIB:EcoCyc10.6'/>, NucR<ref name='LIB:EcoCyc10.6'/>, DeoR<ref name='LIB:EcoCyc10.6'/>, transcriptional repressor for deo operon, tsx, nupG<ref name='LIB:EcoCyc10.6'/>
''ECK0830, b0840, JW0824, nucR''<ref name='LIB:Riley_2006'/>, nucR''
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!{{table_heading_style}} |Description
!align=left {{table_heading_style}} |Product Desc.
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DeoR transcriptional repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
DeoR transcriptional repressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


 
Repressor for deo operon, nupG and tsx; binds deoxyribose-5-phosphate inducer<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
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''DNA-binding transcriptional repressor<ref name='LIB:Riley_2006'/>, B0840<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NucR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DeoR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, transcriptional repressor for deo operon, tsx, nupG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0830, JW0824, nucR, b0840''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!{{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!{{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:txn_units:deoR|deoR]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:deoR|deoR]]<ref name='LIB:EcoCyc10.6'/>  
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!{{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=deoR&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10223]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000217&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=deoR&loc=MG1655%3A881957..881199,W3110%3A883156..882398,DH10B%3A935885..935127,REL606%3A875286..874528,BW2952%3A784167..784925]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=784167&end=784925&gene=deoR&aa=metrreerigqllqelkrsdklhlkdaaallgvsemtirrdlnnhsapvvllggyivleprsashyllsdqksrlveekrraaklaatlvepdqtlffdcgtttpwiieaidneipftavcyslntflalkekphcraflcggefhasnaifkpidfqqtlnnfcpdiafysaagvhvskgatcfnleelpvkhwamsmaqkhvlvvdhskfgkvrparmgdlkrfdivvsdccpedeyvkyaqtqriklmy]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=deoR+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=deoR]]&nbsp;&nbsp;
 
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===Notes===
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==Notes==
 
The ''deoR'' gene is found immediately upstream of the operon. ''DeoR'' encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A ''deoR''-deficient mutant has a high level of ''deoxyriboaldolase'' and ''pyrimidine nucleoside phosphorylase''.  <ref name='PMID:10074062'/>  In ''deoR'' mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)).
 
 
 




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==References==
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Latest revision as of 21:51, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

deoR

Gene Synonym(s)

ECK0830, b0840, JW0824, nucR[1], nucR

Product Desc.

DeoR transcriptional repressor[2][3]

Repressor for deo operon, nupG and tsx; binds deoxyribose-5-phosphate inducer[4]

Product Synonyms(s)

DNA-binding transcriptional repressor[1], B0840[2][1], NucR[2][1], DeoR[2][1], transcriptional repressor for deo operon, tsx, nupG[2][1] , ECK0830, JW0824, nucR, b0840

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): deoR[2]

Regulation/Activity
Quick Links



        

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Notes

[back to top]



The deoR gene is found immediately upstream of the operon. DeoR encodes a repressor protein that negatively regulates the expression of the operon at the level of transcription. A deoR-deficient mutant has a high level of deoxyriboaldolase and pyrimidine nucleoside phosphorylase. [5] In deoR mutations, the repressor is absent and the colonies of the mutants grow more rapidly (Munch-Peterson, et al, Eur. J. Biochem 27: 208-215 (1972)).



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Zeng, X & Saxild, HH (1999) Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis. J. Bacteriol. 181 1719-27 PubMed
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